InjectionClinical Overview
Cefoperazone Sodium is a third-generation parenteral cephalosporin bactericidal antibiotic with notable anti-pseudomonal activity. Unlike most cephalosporins, it is predominantly excreted via the bile, making it exceptionally effective for biliary tract infections and useful in patients with renal impairment without routine dose adjustment. Indicated for biliary infections, peritonitis, respiratory tract infections, and sepsis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered by a licensed clinician via deep intramuscular injection or slow intravenous infusion over 15 to 30 minutes after reconstitution with Water for Injections.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Diarrhea, loose stools, allergic rash, nausea, vomiting. Rare/Severe: Hypoprothrombinemia, bleeding diathesis, disulfiram-like reactions with alcohol, and pseudomembranous colitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Avoid all alcoholic beverages during and for 5 days post-treatment. Monitor coagulation parameters and administer vitamin K if prothrombin time prolongs. Contraindicated in cephalosporin allergy.
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Cefoperazone 1g + Sulbactam 1g Injection
Cefoperazone Sodium and Sulbactam Sodium is a high-potency parenteral combination targeting resistant Gram-negative bacilli and anaerobes. Cefoperazone offers broad anti-pseudomonal and Gram-negative bactericidal coverage excreted primarily via the biliary route, while sulbactam inhibits beta-lactamases and possesses intrinsic activity against Acinetobacter baumannii. Indicated for intra-abdominal infections, biliary tract sepsis, hospital-acquired pneumonia, gynecological infections, and polymicrobial bacteremia.
Cefoperazone 500mg + Sulbactam 500mg Injection
Cefoperazone Sodium and Sulbactam Sodium is a high-potency parenteral combination targeting resistant Gram-negative bacilli and anaerobes. Cefoperazone offers broad anti-pseudomonal and Gram-negative bactericidal coverage excreted primarily via the biliary route, while sulbactam inhibits beta-lactamases and possesses intrinsic activity against Acinetobacter baumannii. Indicated for intra-abdominal infections, biliary tract sepsis, hospital-acquired pneumonia, gynecological infections, and polymicrobial bacteremia.
Cefoperazone 1g + Sulbactam 500mg Injection
Cefoperazone Sodium and Sulbactam Sodium is a high-potency parenteral combination targeting resistant Gram-negative bacilli and anaerobes. Cefoperazone offers broad anti-pseudomonal and Gram-negative bactericidal coverage excreted primarily via the biliary route, while sulbactam inhibits beta-lactamases and possesses intrinsic activity against Acinetobacter baumannii. Indicated for intra-abdominal infections, biliary tract sepsis, hospital-acquired pneumonia, gynecological infections, and polymicrobial bacteremia.
Cefoperazone 2g + Sulbactam 1g Injection
Cefoperazone Sodium and Sulbactam Sodium is a high-potency parenteral combination targeting resistant Gram-negative bacilli and anaerobes. Cefoperazone offers broad anti-pseudomonal and Gram-negative bactericidal coverage excreted primarily via the biliary route, while sulbactam inhibits beta-lactamases and possesses intrinsic activity against Acinetobacter baumannii. Indicated for intra-abdominal infections, biliary tract sepsis, hospital-acquired pneumonia, gynecological infections, and polymicrobial bacteremia.