SprayClinical Overview
Azelastine Hydrochloride (140mcg) and Fluticasone Propionate (50mcg) Nasal Spray is a fixed-dose second-generation H1-antihistamine and corticosteroid combination on the WHO Model List framework. Azelastine provides rapid-onset (within 15 minutes) blockade of histamine H1 receptors, relieving sneezing, nasal itching, and rhinorrhea. Fluticasone provides sustained 24-hour suppression of mucosal inflammation, relieving stubborn nasal congestion. Proven significantly superior to either monotherapy for Moderate-to-Severe Allergic Rhinitis and seasonal rhinoconjunctivitis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Prime spray bottle prior to first use. Blow nose gently. Tilt head slightly forward, insert nozzle into one nostril pointing slightly toward the outer eye (away from nasal septum), spray 1 puff while breathing in gently through the nose, and exhale through the mouth. Repeat in other nostril twice daily (morning and evening). Do NOT sniff hard.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Bitter dysgeusia (bitter taste in mouth in ~10%), epistaxis (mild nosebleeds), nasal burning, headache, somnolence. Rare/Severe: Nasal septal perforation and localized fungal infections.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Point spray AWAY from the nasal septum to prevent septal ulceration or perforation. Tilt head forward during spraying to prevent medicine draining down the throat (avoids bitter taste). Causes mild drowsiness in sensitive individuals.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, pulmonological diagnosis, or respiratory management recommendations. Inhalation therapies and allergy medications should be used strictly under the guidance of a qualified pulmonologist or registered medical practitioner.
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