Clinical Overview
Cefixime is an oral third-generation cephalosporin bactericidal antibiotic. It acts by inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Demonstrates high stability against beta-lactamase enzymes. Indicated for uncomplicated urinary tract infections, otitis media, pharyngitis and tonsillitis, acute exacerbations of chronic bronchitis, uncomplicated gonorrhoea, and enteric (typhoid) fever.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with a glass of water, with or without meals. Taking with food may help decrease stomach irritation. Can be taken once daily or divided into two doses 12 hours apart. Finish the full treatment course.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Diarrhea, loose stools, abdominal pain, nausea, dyspepsia, and flatulence. Rare/Severe: Pseudomembranous colitis, anaphylaxis, Stevens-Johnson syndrome, neutropenia, and acute renal failure.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in cephalosporin allergy. Caution in penicillin-allergic patients (cross-reactivity occurs in 5-10%). Dosage must be adjusted in patients with moderate to severe renal impairment (creatinine clearance < 60 mL/min).
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.