TabletsClinical Overview
Cefixime and Ofloxacin is a fixed-dose combination antibiotic combining a 3rd-generation cephalosporin and a broad-spectrum fluoroquinolone. Cefixime inhibits cell wall synthesis, while ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, halting DNA replication. This dual mechanism provides synergistic bactericidal coverage against resistant pathogens. Indicated for enteric fever (typhoid fever), severe respiratory tract infections, complicated urinary tract infections, and mixed bacterial pelvic infections.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Swallow whole with a full glass of water, with or without meals. Drink plenty of fluids throughout the day. Do not take antacids, sucralfate, or mineral supplements (calcium, iron, zinc) within 2 hours of dosing. Complete the full prescribed course.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, diarrhea, abdominal discomfort, dizziness, headache, and insomnia. Rare/Severe: Tendonitis and tendon rupture, peripheral neuropathy, QT prolongation, central nervous system toxicities, and pseudomembranous colitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Boxed warning for fluoroquinolone-associated tendonitis, neuropathy, and CNS effects. Contraindicated in patients with history of fluoroquinolone tendon disorders, myasthenia gravis, or severe beta-lactam allergy. Not recommended in children, growing adolescents, or pregnancy unless no alternative exists.
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Cefixime Oral Suspension 50mg per 5ml
Cefixime is an oral third-generation cephalosporin bactericidal antibiotic. It acts by inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Demonstrates high stability against beta-lactamase enzymes. Indicated for uncomplicated urinary tract infections, otitis media, pharyngitis and tonsillitis, acute exacerbations of chronic bronchitis, uncomplicated gonorrhoea, and enteric (typhoid) fever.
Cefixime Tablets 100 mg
Cefixime is an oral third-generation cephalosporin bactericidal antibiotic. It acts by inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Demonstrates high stability against beta-lactamase enzymes. Indicated for uncomplicated urinary tract infections, otitis media, pharyngitis and tonsillitis, acute exacerbations of chronic bronchitis, uncomplicated gonorrhoea, and enteric (typhoid) fever.
Cefixime Tablets 200 mg
Cefixime is an oral third-generation cephalosporin bactericidal antibiotic. It acts by inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Demonstrates high stability against beta-lactamase enzymes. Indicated for uncomplicated urinary tract infections, otitis media, pharyngitis and tonsillitis, acute exacerbations of chronic bronchitis, uncomplicated gonorrhoea, and enteric (typhoid) fever.
Ofloxacin 200mg + Ornidazole 500mg Tablets
Ofloxacin and Ornidazole is a broad-spectrum fixed-dose antimicrobial combination pairing a fluoroquinolone with a nitroimidazole. Ofloxacin halts bacterial DNA multiplication, while ornidazole damages microbial DNA through free nitro radicals, eradicating anaerobes and protozoa. Indicated for mixed bacterial and protozoal gastroenteritis, amoebic dysentery, pelvic inflammatory disease, dental infections, and post-surgical abdominal sepsis.