Clinical Overview
Mifepristone Tablets IP 200 mg is a synthetic steroid with potent antiprogestational and antiglucocorticoid activity on the WHO Model List of Essential Medicines. It competitively binds with high affinity to intracellular progesterone receptors, disrupting the decidua, detachment of the blastocyst, and cervical softening. Indicated for medical termination of developing intrauterine pregnancy (in combination with prostaglandin), cervical preparation prior to surgical abortion, and induction of labor in intrauterine fetal death.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally as a single 200 mg dose with water under direct clinical supervision. Followed 24 to 48 hours later by prostaglandin (e.g. misoprostol 800 mcg) as prescribed. Ultrasound confirmation of gestational age and intrauterine location is mandatory prior to dosing.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Vaginal bleeding, uterine cramping, abdominal pain, nausea, vomiting, headache, weakness, dizziness. Rare/Severe: Uncontrolled hemorrhage, pelvic sepsis, unrecognized ruptured ectopic pregnancy, and severe allergic angioedema.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in suspected ectopic pregnancy, chronic adrenal failure, concurrent long-term corticosteroid therapy, known coagulopathies, and severe uncontrolled asthma. Incomplete abortion requires surgical intervention.
Schedule H (Prescription Required - MTP Act Compliant)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.