TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2854.
Locate Jan Aushadhi KendraClinical Overview
Safinamide is a multimodal agent with dual mechanisms of action: potent, selective, and reversible inhibition of monoamine oxidase B (MAO-B), combined with state- and use-dependent blockade of voltage-gated sodium channels and inhibition of stimulated glutamate release. Indicated as add-on therapy to a stable dose of levodopa/carbidopa in Parkinson's disease patients experiencing "off" episodes.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily at the same time every day with water, with or without food. Do not exceed 100 mg/day.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dyskinesia, somnolence, dizziness, nausea, insomnia, orthostatic hypotension, falls. Rare/Severe: Hypertensive crisis, Serotonin Syndrome, retinal degeneration, and impulse control disorders.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated with other MAO inhibitors, pethidine, and dextromethorphan. Contraindicated in severe hepatic impairment. Periodic retinal monitoring is advised in patients with retinal disease.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.