InjectionMRP Under Process
Official PMBI MRP is being updated for catalog code 2801.
Locate Jan Aushadhi KendraClinical Overview
Carbetocin Injection 100 mcg/ml is a synthetic, long-acting nonapeptide analogue of human oxytocin on the WHO Model List of Essential Medicines. It possesses structural modifications that provide resistance to enzymatic degradation, conferring a half-life of ~40 minutes (4 to 10 times longer than oxytocin) and generating continuous rhythmic uterine contractions for several hours. Indicated for the prevention of postpartum hemorrhage (PPH) due to uterine atony following vaginal birth or cesarean delivery under epidural or spinal anesthesia.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administer as a single slow intravenous (IV) bolus dose over 1 minute (or single intramuscular injection following vaginal delivery) immediately after delivery of the infant, preferably before removal of the placenta. Single dose only; do not administer repeat doses. If uterine atony persists, switch to secondary uterotonic agents (ergot alkaloids, prostaglandins).
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, abdominal pain, pruritus, flushing, feeling of warmth, headache, tremor, hypotension, dizziness, and metallic taste. Rare/Severe: Severe hypotension, tachycardia, arrhythmia, chest pain, and water intoxication/hyponatremia (mild antidiuretic activity).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated during pregnancy and labor prior to delivery of the infant; contraindicated in patients with severe cardiovascular disease, epilepsy, hepatic/renal dysfunction, or hypersensitivity. Do not use for induction or augmentation of labor.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.