TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2625.
Locate Jan Aushadhi KendraClinical Overview
Rasagiline is a second-generation, irreversible, selective monoamine oxidase type B (MAO-B) inhibitor. It prevents the metabolic breakdown of dopamine in the striatum, increasing synaptic dopamine concentrations without the amphetamine metabolites associated with selegiline. Indicated as initial monotherapy in early Parkinson's disease and as adjunctive therapy to levodopa in advanced disease with motor fluctuations.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily with water, with or without food. Swallow whole. Adhere strictly to the once-daily schedule.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Headache, nausea, dyspepsia, joint pain, dizziness, insomnia, postural hypotension. Rare/Severe: Hypertensive crisis (at supratherapeutic doses or with excessive tyramine intake), Serotonin Syndrome when combined with serotonergic drugs, and dyskinesia exacerbation with levodopa.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated with meperidine, tramadol, methadone, St. John's wort, cyclobenzaprine, and other MAO inhibitors due to fatal serotonin syndrome or hypertensive crisis. Caution with concurrent SSRIs and SNRIs. Avoid tyramine-rich foods if taking doses > 1 mg/day.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.