Clinical Overview
Azelaic Acid (10%, 20% cream) is a naturally occurring saturated dicarboxylic acid anti-acne and anti-rosacea agent. It inhibits DNA synthesis in Cutibacterium acnes, suppresses follicular hyperkeratinization (comedolytic), and competitively inhibits tyrosinase, reducing post-inflammatory hyperpigmentation without bleaching normal skin. Indicated for mild-to-moderate inflammatory acne vulgaris, papulopustular rosacea, and post-inflammatory hyperpigmentation/melasma.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Wash affected area with water or mild soap and pat dry. Apply a thin layer twice daily (morning and evening) and massage gently. If severe irritation occurs, reduce to once daily until irritation subsides.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild transient burning, stinging, tingling, pruritus, localized dryness. Rare/Severe: Allergic contact dermatitis, worsening of asthma.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
For external cutaneous use only. Avoid contact with eyes, nose, and mouth. Safe for use during pregnancy when clinically indicated.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered dermatologist or qualified medical practitioner before initiating, altering, or substituting any topical or systemic dermatological treatment.