TabletsClinical Overview
Micronized Purified Flavonoid Fraction (MPFF; Diosmin 90% and Hesperidin 10%) is an oral phlebotropic and vascular-protective agent. Micronization reduces particle size (< 2 micrometers), drastically enhancing intestinal absorption. It increases venous tone by prolonging noradrenergic activity on venous walls, enhances lymphatic drainage, protects microvascular capillaries against hyperpermeability, and inhibits leukocyte adhesion and activation, mitigating chronic venous inflammation. Indicated for chronic venous insufficiency (CVI; varicose veins, venous ulcers, heaviness, leg swelling) and acute hemorrhoidal attacks.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with meals with water, divided into two doses daily (midday and evening). For acute hemorrhoidal crises, higher doses are taken for the first 4 days as prescribed, followed by standard maintenance.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dyspepsia, nausea, diarrhea, abdominal discomfort, headache, malaise. Rare/Severe: Angioedema, allergic dermatitis, and dizziness.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Does not replace specific proctological treatment for other anal disorders. In chronic venous disease, combine with lifestyle measures (compression stockings, leg elevation, avoiding prolonged standing).
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.