TabletsClinical Overview
Paroxetine is a phenylpiperidine-derivative selective serotonin reuptake inhibitor (SSRI) with the highest affinity for SERT among all SSRIs. It also exhibits mild anticholinergic and nitric oxide synthase-inhibiting properties. Prolonged-release formulation ensures gradual drug release over 24 hours, mitigating peak-related gastrointestinal and sedative adverse effects. Indicated for major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, and PTSD.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Swallow prolonged-release tablets whole with water in the morning, with or without breakfast. Do not chew, crush, or break tablets. Strict adherence is vital; missing a single dose can precipitate severe discontinuation syndrome.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, somnolence, sweating, tremor, asthenia, dry mouth, constipation, sexual dysfunction (erectile dysfunction, anorgasmia), weight gain. Rare/Severe: Severe discontinuation syndrome (electric shock sensations, dizziness), suicidal thoughts, serotonin syndrome, and teratogenicity (cardiac defects).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Boxed warning for suicidality in young patients. Contraindicated in pregnancy (Category D: congenital cardiac malformations). Severe discontinuation syndrome upon sudden cessation; requires slow, meticulous tapering. Avoid concurrent MAOIs.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Paroxetine Prolonged Release Tablets 37.5mg
Paroxetine is a phenylpiperidine-derivative selective serotonin reuptake inhibitor (SSRI) with the highest affinity for SERT among all SSRIs. It also exhibits mild anticholinergic and nitric oxide synthase-inhibiting properties. Prolonged-release formulation ensures gradual drug release over 24 hours, mitigating peak-related gastrointestinal and sedative adverse effects. Indicated for major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, and PTSD.
Paroxetine Extended Release 12.5mg + Clonazepam 0.25mg Tablets
Clonazepam is a long-acting benzodiazepine with potent anticonvulsant, muscle-relaxant, and anxiolytic actions on the WHO Model List of Essential Medicines. It allosterically modulates GABAA receptors, increasing frequency of chloride channel opening and dampening epileptic foci in the cortex and limbic system. Indicated for panic disorder with or without agoraphobia, Lennox-Gastaut syndrome, myoclonic and akinetic seizures, and absence seizures refractory to succinimides.
Paroxetine Prolonged-release Tablets 12.5mg
Paroxetine is a phenylpiperidine-derivative selective serotonin reuptake inhibitor (SSRI) with the highest affinity for SERT among all SSRIs. It also exhibits mild anticholinergic and nitric oxide synthase-inhibiting properties. Prolonged-release formulation ensures gradual drug release over 24 hours, mitigating peak-related gastrointestinal and sedative adverse effects. Indicated for major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, and PTSD.