Clinical Overview
Estradiol Tablets 2 mg is a bioidentical 17-beta-estradiol formulation identical to endogenous human ovarian estradiol. It restores estrogen receptor activation in the brain, bone, urogenital tract, and cardiovascular system. Indicated for the relief of menopausal symptoms (hot flushes, night sweats, sleep disturbances), management of hypoestrogenism (oophorectomy, primary ovarian insufficiency), endometrial priming in assisted reproduction (frozen embryo transfer / donor egg IVF cycles), and prevention of postmenopausal bone loss.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 to 2 mg once daily with water at the same time each day, continuously or sequentially as directed by the gynecologist. In women with an intact uterus, sequential or continuous-combined progestogen therapy is mandatory. For IVF endometrial preparation: taken as escalating or fixed daily doses as specified by ART protocol until adequate endometrial stripe thickness (>=8mm) is verified on transvaginal ultrasound.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Breast tenderness, nausea, headache, fluid retention, mood changes, and breakthrough bleeding. Rare/Severe: Thromboembolism (DVT, PE, retinal thrombosis), endometrial hyperplasia/carcinoma (without progestogen), ischemic stroke, and cholestatic jaundice.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Cardiovascular disorders, breast cancer, endometrial cancer, and dementia risks with long-term HRT. Contraindicated in active or past thromboembolism, ischemic heart disease, active liver disease, porphyria, and suspected hormone-sensitive neoplasms. Regular mammography and gynecological evaluation mandatory.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.