TabletsClinical Overview
Omeprazole Gastro-Resistant Capsules (20mg) is a prototypical proton pump inhibitor on the WHO Model List of Essential Medicines. It enters parietal cell canaliculi as a prodrug where acidic pH converts it to a tetracyclic sulfenamide that permanently inactivates H+/K+-ATPase pumps. Indicated for duodenal ulcers, benign gastric ulcers, reflux esophagitis, maintenance therapy of healed erosive esophagitis, and H. pylori eradication (as part of triple therapy).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily in the morning, 30 to 60 minutes before breakfast. Swallow whole with water; do not crush or chew the pellets inside the capsule. For patients with swallowing difficulty, capsule contents can be mixed into a tablespoon of applesauce and swallowed immediately without chewing.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Headache, abdominal pain, constipation, diarrhea, flatulence, nausea/vomiting. Rare/Severe: Acute interstitial nephritis, Clostridioides difficile colitis, hypomagnesemia, hip/wrist/spine fractures (chronic use), and cutaneous lupus.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Inhibits CYP2C19; clinically significant interaction with clopidogrel (decreases active clopidogrel metabolite and antiplatelet efficacy; pantoprazole preferred in dual antiplatelet therapy) and increases levels of phenytoin, warfarin, and diazepam.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.
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