TabletsClinical Overview
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). It antagonizes presynaptic alpha-2 auto- and hetero-receptors, boosting central release of both norepinephrine and serotonin. It selectively blocks postsynaptic 5-HT2 and 5-HT3 receptors (sparing patients from SSRI-associated nausea, anxiety, and sexual dysfunction) while enhancing 5-HT1A-mediated transmission. It is also a potent H1 antagonist. Indicated for major depressive disorder, particularly in patients with severe insomnia, anxiety, and weight loss.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily as a single dose immediately before bedtime with a glass of water, with or without food. Mouth-dissolving tablets can be placed on the tongue. Do not crush. Taper gradually when stopping.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, sedation, increased appetite, weight gain, dry mouth, constipation, dizziness. Rare/Severe: Boxed warning: Suicidal ideation; agranulocytosis/neutropenia, severe neutropenic infection, angle-closure glaucoma, and hyponatremia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning for suicidality in young patients. Patients must report any sudden sore throat, mouth ulcers, or fever immediately to evaluate for agranulocytosis. Contraindicated with MAOIs. Caution with driving due to pronounced sedation.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Mirtazapine Tablets 15mg
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). It antagonizes presynaptic alpha-2 auto- and hetero-receptors, boosting central release of both norepinephrine and serotonin. It selectively blocks postsynaptic 5-HT2 and 5-HT3 receptors (sparing patients from SSRI-associated nausea, anxiety, and sexual dysfunction) while enhancing 5-HT1A-mediated transmission. It is also a potent H1 antagonist. Indicated for major depressive disorder, particularly in patients with severe insomnia, anxiety, and weight loss.
Mirtazapine Tablets 7.5mg
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). It antagonizes presynaptic alpha-2 auto- and hetero-receptors, boosting central release of both norepinephrine and serotonin. It selectively blocks postsynaptic 5-HT2 and 5-HT3 receptors (sparing patients from SSRI-associated nausea, anxiety, and sexual dysfunction) while enhancing 5-HT1A-mediated transmission. It is also a potent H1 antagonist. Indicated for major depressive disorder, particularly in patients with severe insomnia, anxiety, and weight loss.