Clinical Overview
Famotidine Tablets (20mg, 40mg) is a potent, highly selective competitive histamine H2-receptor antagonist on the WHO Model List of Essential Medicines. It is approximately 8 times more potent than ranitidine and 30 times more potent than cimetidine on a weight basis, without binding to hepatic cytochrome P450 enzymes or displaying antiandrogenic activity. Indicated for short-term treatment of active duodenal ulcer, active benign gastric ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily at bedtime (40 mg for active ulcers) or 20 mg twice daily (morning and evening) with a glass of water, with or without food. For heartburn prevention, take 10-20 mg 15 to 60 minutes before meals likely to cause symptoms.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Headache, dizziness, constipation, diarrhea. Rare/Severe: Confusion, agitation, hallucinations (especially in elderly or renally impaired patients), thrombocytopenia, and hypersensitivity.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Unlike cimetidine, famotidine does not inhibit CYP450 enzymes and has negligible drug-drug interactions. Reduce dosage by 50% in patients with moderate to severe renal impairment (CrCl < 50 mL/min).
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or gastrointestinal treatment recommendations. Always consult a registered gastroenterologist or qualified medical practitioner before initiating, altering, or discontinuing any gastrointestinal medication or digestive therapy.