TabletsClinical Overview
Amoxapine is a tricyclic dibenzoxazepine antidepressant. In addition to inhibiting norepinephrine and serotonin reuptake, its active 7-hydroxy metabolite produces significant blockade of dopamine D2 receptors, conferring unique antipsychotic properties. Indicated for major depressive disorder with psychotic features (delusional depression) and neurotic depression.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with water, divided throughout the day or as a single bedtime dose. Take with meals to reduce gastric upset. Taper gradually.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Sedation, dry mouth, constipation, blurred vision, dizziness. Rare/Severe: Extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome (NMS), seizures, and hyperprolactinemia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Unique among TCAs in possessing neuroleptic risks (tardive dyskinesia, NMS) due to dopamine receptor blockade. Contraindicated in acute post-MI and with MAOIs.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.