Clinical Overview
Alfuzosin Prolonged-Release Tablets (10mg) is a quinazoline-derivative, functionally uroselective alpha-1 adrenergic antagonist on the WHO Model List framework. It distributes preferential clinical relaxant action to prostatic and trigonal smooth muscle, reducing bladder outlet obstruction without predominantly altering ejaculatory duct innervation, resulting in a very low incidence of retrograde ejaculation (<1-2%). Indicated for the treatment of moderate-to-severe symptoms of Benign Prostatic Hyperplasia (BPH) and as adjunctive therapy with catheterization for acute urinary retention related to BPH.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 10 mg once daily immediately after the same meal each day (preferably dinner) with water. Swallow the tablet whole; do not bite, crush, or divide.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dizziness, headache, fatigue, upper respiratory tract infection, nausea, abdominal pain. Rare/Severe: Orthostatic hypotension, syncope, QT prolongation, hepatotoxicity, and priapism.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in moderate or severe hepatic impairment and with potent CYP3A4 inhibitors. Alfuzosin carries a modest QT-prolonging potential; use caution in patients with congenital long QT syndrome. Low risk of sexual/ejaculatory dysfunction compared to tamsulosin and silodosin.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, nephrological diagnosis, or urological treatment recommendations. Always consult a registered nephrologist, urologist, or qualified medical practitioner before initiating, modifying, or discontinuing any kidney or urinary tract medication.