Clinical Overview
Torsemide / Torasemide Tablets (5mg, 40mg) is a long-acting pyridine-sulfonylurea loop diuretic on the WHO Model List framework. It inhibits the Na+/K+/2Cl- carrier system in the thick ascending limb of Henle's loop, blocking active sodium and chloride reabsorption. It features high oral bioavailability (~80%), consistent absorption regardless of intestinal mucosal edema, and an extended duration of action (~12 hours) with anti-aldosteronergic properties that cause less potassium wasting than furosemide. Indicated for treatment of edema associated with congestive heart failure, chronic kidney disease (CKD), nephrotic syndrome, hepatic cirrhosis, and management of hypertension.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Edema: Take orally 10 mg to 20 mg once daily in the morning with water; titrate up to 40 mg to 100 mg daily in renal impairment. Hypertension: 2.5 mg to 5 mg once daily. Morning administration is strongly advised to prevent nighttime urination.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Polyuria, dizziness, headache, dehydration, mild hypokalemia, hyponatremia. Rare/Severe: Severe electrolyte depletion, hypotension, ototoxicity (tinnitus, hearing loss with high doses in renal failure), and acute kidney injury.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in anuria, hepatic coma, and severe hypokalemia/hyponatremia. Monitor serum electrolytes (potassium, sodium), BUN, and creatinine routinely. Caution in patients with gout (may elevate uric acid).
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, nephrological diagnosis, or urological treatment recommendations. Always consult a registered nephrologist, urologist, or qualified medical practitioner before initiating, modifying, or discontinuing any kidney or urinary tract medication.
Torsemide Tablets 20 mg
Torsemide Tablets 20 mg is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.
Torsemide 10mg + Spironolactone 50mg Tablets
Spironolactone is a synthetic steroid competitive mineralocorticoid receptor (aldosterone) antagonist and potassium-sparing diuretic on the WHO Model List of Essential Medicines. It blocks aldosterone binding in the late distal renal tubules and cortical collecting ducts, increasing sodium and water excretion while conserving potassium and hydrogen ions. In heart failure, it blocks aldosterone-mediated myocardial fibrosis and endothelial dysfunction. Indicated for heart failure with reduced ejection fraction (NYHA class II-IV), primary hyperaldosteronism, cirrhosis with ascites, resistant hypertension, and nephrotic edema.
Torsemide Tablets 5mg
Torsemide / Torasemide Tablets (5mg, 40mg) is a long-acting pyridine-sulfonylurea loop diuretic on the WHO Model List framework. It inhibits the Na+/K+/2Cl- carrier system in the thick ascending limb of Henle's loop, blocking active sodium and chloride reabsorption. It features high oral bioavailability (~80%), consistent absorption regardless of intestinal mucosal edema, and an extended duration of action (~12 hours) with anti-aldosteronergic properties that cause less potassium wasting than furosemide. Indicated for treatment of edema associated with congestive heart failure, chronic kidney disease (CKD), nephrotic syndrome, hepatic cirrhosis, and management of hypertension.
Torsemide Tablets 100mg
Torsemide Tablets 100mg is an evidence-based cardiovascular and hemodynamic pharmaceutical formulation. It acts by modulating vascular smooth muscle tone, autonomic receptors, or fluid-electrolyte balance to manage cardiovascular disease.