TabletsClinical Overview
Prasugrel Hydrochloride is a third-generation oral thienopyridine prodrug that irreversibly blocks the platelet P2Y12 ADP receptor. It undergoes single-step CYP450 bioactivation (primarily CYP3A4 and CYP2B6), achieving more rapid, potent, and consistent platelet inhibition than clopidogrel with minimal resistance. Indicated for the prevention of atherothrombotic events in patients with acute coronary syndrome undergoing percutaneous coronary intervention (PCI).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily with water, with or without meals, alongside low-dose aspirin. Take at the same time each day. Maintain therapy for the full prescribed duration.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Bleeding, epistaxis, hematoma, gastrointestinal bleeding, anemia. Rare/Severe: Boxed warning: Significant, sometimes fatal, major bleeding; thrombotic thrombocytopenic purpura (TTP).
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Major bleeding risk. Strictly contraindicated in patients with a history of stroke or transient ischemic attack (TIA) due to unacceptable intracranial hemorrhage risk. Not recommended in patients aged >= 75 years or weighing < 60 kg unless under specialized dose reduction.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.