Clinical Overview
Ethinylestradiol 0.03 mg and Desogestrel 0.15 mg Tablets is a third-generation low-dose monophasic Combined Oral Contraceptive (COC) pill on the WHO Model List of Essential Medicines. It prevents pregnancy primarily by suppressing pituitary gonadotropin secretion (inhibiting ovulation), thickening cervical mucus to prevent sperm penetration, and altering the endometrium to impair implantation. Desogestrel has high progestogenic potency and low androgenic activity, causing less acne and weight gain than older progestogens.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally 1 tablet daily at the same hour each day for 21 consecutive days, followed by a 7-day tablet-free interval. Restart next cycle on the 8th day without interruption. If a pill is missed: take it as soon as remembered and consult packaging rules (use backup barrier contraception for 7 days if missed by >12 hours).
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, breakthrough bleeding/spotting, headache, breast tension, mood changes, and fluid retention. Rare/Severe: Venous thromboembolism (DVT, PE), stroke, myocardial infarction, hypertension, and cholelithiasis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Cigarette smoking significantly increases the risk of serious cardiovascular events from oral contraceptive use; strongly contraindicated in women over 35 who smoke. Contraindicated in thrombophlebitis, thromboembolic disorders, estrogen-dependent neoplasms, undiagnosed abnormal vaginal bleeding, and active hepatic disease.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.