Clinical Overview
Sertraline Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) on the WHO Model List of Essential Medicines. It selectively inhibits the membrane transporter SERT, increasing synaptic serotonin concentrations. Also exhibits weak dopamine reuptake inhibition (DAT), which may assist with fatigue and cognitive slowing. Favored in cardiac patients due to low arrhythmogenic risk. Indicated for major depressive disorder, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and social anxiety disorder.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily, in the morning or evening, with or without food. Swallow whole with water. Dose adjustments should occur at intervals of at least 1 week. Taper gradually when discontinuing.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, diarrhea, loose stools, dyspepsia, insomnia, dizziness, somnolence, sexual dysfunction. Rare/Severe: Boxed warning: Suicidal ideation in young patients; serotonin syndrome, platelet dysfunction/bleeding, and angle-closure glaucoma.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning for suicidality in adolescents and young adults. Contraindicated with MAO inhibitors or pimozide. Caution when combining with anticoagulants, antiplatelets, or NSAIDs due to bleeding risks.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Sertraline Tablets 100mg
Sertraline Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) on the WHO Model List of Essential Medicines. It selectively inhibits the membrane transporter SERT, increasing synaptic serotonin concentrations. Also exhibits weak dopamine reuptake inhibition (DAT), which may assist with fatigue and cognitive slowing. Favored in cardiac patients due to low arrhythmogenic risk. Indicated for major depressive disorder, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and social anxiety disorder.
Sertraline Tablets 25mg
Sertraline Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) on the WHO Model List of Essential Medicines. It selectively inhibits the membrane transporter SERT, increasing synaptic serotonin concentrations. Also exhibits weak dopamine reuptake inhibition (DAT), which may assist with fatigue and cognitive slowing. Favored in cardiac patients due to low arrhythmogenic risk. Indicated for major depressive disorder, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and social anxiety disorder.
Alprazolam 0.5mg + Sertraline Hydrochloride 25mg Tablets
Alprazolam and Sertraline pairs an immediate-acting high-potency benzodiazepine with an SSRI. Alprazolam bridges the initial 2-4 week lag phase of antidepressant therapy by rapidly controlling severe anxiety, panicky distress, and insomnia, while sertraline elevates synaptic serotonin to alleviate core depressive illness. Indicated for major depressive episodes accompanied by prominent anxiety symptoms.
Alprazolam 0.5mg + Sertraline Hydrochloride 50mg Tablets
Alprazolam and Sertraline pairs an immediate-acting high-potency benzodiazepine with an SSRI. Alprazolam bridges the initial 2-4 week lag phase of antidepressant therapy by rapidly controlling severe anxiety, panicky distress, and insomnia, while sertraline elevates synaptic serotonin to alleviate core depressive illness. Indicated for major depressive episodes accompanied by prominent anxiety symptoms.