TabletsClinical Overview
Quetiapine Fumarate is a dibenzothiazepine atypical antipsychotic. It exhibits antagonist activity at serotonin 5-HT2A and dopamine D2 receptors, with rapid dissociation from D2 receptors ("hit-and-run" kinetics) which minimizes extrapyramidal symptoms and hyperprolactinemia. Its active metabolite, norquetiapine, potently inhibits norepinephrine reuptake (NET) and acts as a 5-HT1A partial agonist, conferring distinctive antidepressant efficacy. Indicated for schizophrenia, acute manic episodes in bipolar I disorder, bipolar depression, and adjunctive therapy in major depressive disorder.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with water, divided twice daily or as a single bedtime dose, with or without food. Swallow whole; do not crush or chew prolonged-release forms. Dose titration must be followed carefully.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, sedation, dry mouth, dizziness, weight gain, constipation, tachycardia, orthostatic hypotension. Rare/Severe: Boxed warning: Increased mortality in elderly dementia patients and suicidality in young adults; neuroleptic malignant syndrome, tardive dyskinesia, cataracts, and severe hyperglycemia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Boxed warnings for dementia-related psychosis and antidepressant suicidality. Baseline and periodic slit-lamp ophthalmologic examinations recommended to screen for lens changes. Monitor fasting lipids and blood glucose.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Quetiapine Fumarate Tablets 200mg
Quetiapine Fumarate is a dibenzothiazepine atypical antipsychotic. It exhibits antagonist activity at serotonin 5-HT2A and dopamine D2 receptors, with rapid dissociation from D2 receptors ("hit-and-run" kinetics) which minimizes extrapyramidal symptoms and hyperprolactinemia. Its active metabolite, norquetiapine, potently inhibits norepinephrine reuptake (NET) and acts as a 5-HT1A partial agonist, conferring distinctive antidepressant efficacy. Indicated for schizophrenia, acute manic episodes in bipolar I disorder, bipolar depression, and adjunctive therapy in major depressive disorder.
Quetiapine Tablets 25 mg
Quetiapine Fumarate is a dibenzothiazepine atypical antipsychotic. It exhibits antagonist activity at serotonin 5-HT2A and dopamine D2 receptors, with rapid dissociation from D2 receptors ("hit-and-run" kinetics) which minimizes extrapyramidal symptoms and hyperprolactinemia. Its active metabolite, norquetiapine, potently inhibits norepinephrine reuptake (NET) and acts as a 5-HT1A partial agonist, conferring distinctive antidepressant efficacy. Indicated for schizophrenia, acute manic episodes in bipolar I disorder, bipolar depression, and adjunctive therapy in major depressive disorder.
Quetiapine Tablets 50mg
Quetiapine Fumarate is a dibenzothiazepine atypical antipsychotic. It exhibits antagonist activity at serotonin 5-HT2A and dopamine D2 receptors, with rapid dissociation from D2 receptors ("hit-and-run" kinetics) which minimizes extrapyramidal symptoms and hyperprolactinemia. Its active metabolite, norquetiapine, potently inhibits norepinephrine reuptake (NET) and acts as a 5-HT1A partial agonist, conferring distinctive antidepressant efficacy. Indicated for schizophrenia, acute manic episodes in bipolar I disorder, bipolar depression, and adjunctive therapy in major depressive disorder.
Quetiapine Prolonged release Tablets 300mg
Quetiapine Fumarate is a dibenzothiazepine atypical antipsychotic. It exhibits antagonist activity at serotonin 5-HT2A and dopamine D2 receptors, with rapid dissociation from D2 receptors ("hit-and-run" kinetics) which minimizes extrapyramidal symptoms and hyperprolactinemia. Its active metabolite, norquetiapine, potently inhibits norepinephrine reuptake (NET) and acts as a 5-HT1A partial agonist, conferring distinctive antidepressant efficacy. Indicated for schizophrenia, acute manic episodes in bipolar I disorder, bipolar depression, and adjunctive therapy in major depressive disorder.