Topiroxostat
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Pain, Fever & Arthritis treatment.
🧴 Clinical Application
Take orally 20 mg twice daily with water, titrated up to 40 mg to 60 mg twice daily based on serum uric acid target (<6.0 mg/dL). Can be taken with or without food.
⚠️ Side Effects
Common: Initial gout flares, transaminase elevations, mild dizziness, gastrointestinal discomfort. Rare/Severe: Severe allergic reactions and cardiovascular events.
🛡️ Safety Warnings
Co-administer prophylactic anti-gout therapy during initial months. Contraindicated with azathioprine or mercaptopurine. Safe in moderate chronic kidney disease.
Jan Aushadhi Products containing Topiroxostat
Found 3 generic formulation(s) containing this active ingredient.
Topiroxostat Tablets 20mg
Topiroxostat Tablets (20mg, 40mg, 60mg) is a novel non-purine selective xanthine oxidoreductase (XOR) inhibitor on the PMBI formulary. It inhibits both the xanthine dehydrogenase and xanthine oxidase forms of the enzyme by interacting with multiple amino acid residues in the solvent-accessible channel, reducing uric acid production and oxidative stress with exceptional renal safety. Indicated for hyperuricemia with or without gout in patients with chronic kidney disease (CKD stage 3).
Topiroxostat Tablets 40mg
Topiroxostat Tablets (20mg, 40mg, 60mg) is a novel non-purine selective xanthine oxidoreductase (XOR) inhibitor on the PMBI formulary. It inhibits both the xanthine dehydrogenase and xanthine oxidase forms of the enzyme by interacting with multiple amino acid residues in the solvent-accessible channel, reducing uric acid production and oxidative stress with exceptional renal safety. Indicated for hyperuricemia with or without gout in patients with chronic kidney disease (CKD stage 3).
Topiroxostat Tablets 60mg
Topiroxostat Tablets (20mg, 40mg, 60mg) is a novel non-purine selective xanthine oxidoreductase (XOR) inhibitor on the PMBI formulary. It inhibits both the xanthine dehydrogenase and xanthine oxidase forms of the enzyme by interacting with multiple amino acid residues in the solvent-accessible channel, reducing uric acid production and oxidative stress with exceptional renal safety. Indicated for hyperuricemia with or without gout in patients with chronic kidney disease (CKD stage 3).
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Topiroxostat.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Topiroxostat Tablets 20mg | 10's | ₹46.88 | TOPIROXO | ₹108.90 | 57% Save |
| Topiroxostat Tablets 40mg | 10's | ₹84.38 | TOPIROXO, XORI | ₹181.22 | 53% Save |
| Topiroxostat Tablets 60mg | 10's | ₹121.88 | Topimac, Toxur | ₹188.00 | 35% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Topiroxostat generics.