Topiramate
Active pharmaceutical substance formulated in Jan Aushadhi generic products for CNS, Nerve & Mental Health treatment.
🧴 Clinical Application
Swallow tablets whole with water; do not break or chew due to an intense bitter taste. Can be taken with or without food. Maintain abundant daily fluid intake (at least 2-3 liters) to prevent kidney stone formation. Titrate slowly.
⚠️ Side Effects
Common: Paresthesia (tingling in fingers/toes), cognitive slowing, word-finding difficulty, memory impairment, anorexia, weight loss, somnolence, fatigue. Rare/Severe: Acute secondary angle-closure glaucoma and acute myopia, oligohidrosis (reduced sweating) and hyperthermia, metabolic acidosis (via carbonic anhydrase inhibition), nephrolithiasis (kidney stones), and teratogenicity (cleft lip/palate).
🛡️ Safety Warnings
Patients experiencing sudden eye pain, redness, or blurred vision must stop immediately and seek emergency ophthalmological care (risk of permanent blindness from angle-closure glaucoma). Ensure high fluid intake to prevent kidney stones. Contraindicated in pregnancy for migraine prophylaxis due to oral cleft risk.
Jan Aushadhi Products containing Topiramate
Found 2 generic formulation(s) containing this active ingredient.
Topiramate 100mg Tablets
Topiramate is a sulfamate-substituted monosaccharide antiepileptic with multiple mechanisms of action. It blocks voltage-dependent sodium channels, potentiates GABA-mediated inhibitory currents at non-benzodiazepine sites, antagonizes AMPA/kainate glutamate receptors, and weakly inhibits carbonic anhydrase isozymes CA-II and CA-IV. Indicated for partial-onset seizures, primary generalized tonic-clonic seizures, Lennox-Gastaut syndrome, and migraine prophylaxis in adults and adolescents.
Topiramate 50mg Tablets
Topiramate is a sulfamate-substituted monosaccharide antiepileptic with multiple mechanisms of action. It blocks voltage-dependent sodium channels, potentiates GABA-mediated inhibitory currents at non-benzodiazepine sites, antagonizes AMPA/kainate glutamate receptors, and weakly inhibits carbonic anhydrase isozymes CA-II and CA-IV. Indicated for partial-onset seizures, primary generalized tonic-clonic seizures, Lennox-Gastaut syndrome, and migraine prophylaxis in adults and adolescents.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Topiramate.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Topiramate 100mg Tablets | 10's | ₹28.13 | TOPAZ, TOPAMAC, TOPIROL, TOPAMED, LEPTOMATE | ₹303.75 | 91% Save |
| Topiramate 50mg Tablets | 10's | ₹18.75 | TOPAZ, TOPAMAC, TOPIROL, TOPIRANOL, NEXTOP | ₹165.54 | 89% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Topiramate generics.