Tapentadol
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Pain, Fever & Arthritis treatment.
🧴 Clinical Application
IR: 50 mg to 100 mg orally every 4 to 6 hours as needed (maximum 500 mg on day 1, 400 mg daily thereafter). ER: 100 mg orally every 12 hours with water, swallowed whole; do NOT crush, chew, or divide. Take with or without food.
⚠️ Side Effects
Common: Nausea, dizziness, somnolence, constipation, headache, vomiting, pruritus. Rare/Severe: Life-threatening respiratory depression, severe hypotension, syncope, seizures, and addiction/abuse liability.
🛡️ Safety Warnings
Schedule H1 / Controlled Substance: High potential for abuse and respiratory depression; monitor closely. Extended-release tablets must be swallowed whole; crushing releases a fatal opioid bolus. Contraindicated in severe respiratory depression, paralytic ileus, or concomitant MAO inhibitors (within 14 days).
Jan Aushadhi Products containing Tapentadol
Found 2 generic formulation(s) containing this active ingredient.
Tapentadol 100mg Extended Release Tablets
Tapentadol Tablets (50mg immediate-release, 100mg extended-release) is a centrally acting synthetic analgesic with a dual mechanism: potent mu-opioid receptor agonism (MOR) and noradrenaline reuptake inhibition (NRI). Unlike tramadol, it has minimal serotonergic activity (virtually eliminating serotonin syndrome risk) and does not rely on metabolic CYP2D6 bioactivation for efficacy, producing consistent and predictable analgesia. Indicated for management of severe acute pain (immediate-release) and severe chronic pain / painful diabetic peripheral neuropathy (extended-release).
Tapentadol 50mg Tablets
Tapentadol Tablets (50mg immediate-release, 100mg extended-release) is a centrally acting synthetic analgesic with a dual mechanism: potent mu-opioid receptor agonism (MOR) and noradrenaline reuptake inhibition (NRI). Unlike tramadol, it has minimal serotonergic activity (virtually eliminating serotonin syndrome risk) and does not rely on metabolic CYP2D6 bioactivation for efficacy, producing consistent and predictable analgesia. Indicated for management of severe acute pain (immediate-release) and severe chronic pain / painful diabetic peripheral neuropathy (extended-release).
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Tapentadol.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Tapentadol 100mg Extended Release Tablets | 10's | ₹67.03 | N/A | N/A | N/A |
| Tapentadol 50mg Tablets | 10's | ₹30.00 | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Tapentadol generics.