Silodosin
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Kidney & Urinary Care treatment.
🧴 Clinical Application
Take orally once daily with a meal (8 mg once daily with dinner; 4 mg once daily in moderate renal impairment CrCl 30-50 mL/min) with a glass of water. Swallow whole.
⚠️ Side Effects
Common: Retrograde ejaculation (anejaculation occurring in up to 28% of patients), dizziness, diarrhea, orthostatic dizziness, nasopharyngitis. Rare/Severe: Intraoperative Floppy Iris Syndrome (IFIS) and priapism.
🛡️ Safety Warnings
High incidence of retrograde ejaculation; counsel patients that semen enters the bladder during climax without affecting sexual pleasure or orgasmic function. Contraindicated in severe renal impairment (CrCl < 30 mL/min) and severe hepatic impairment (Child-Pugh C). Contraindicated with strong CYP3A4 inhibitors (clarithromycin, ketoconazole).
Jan Aushadhi Products containing Silodosin
Found 4 generic formulation(s) containing this active ingredient.
Silodosin Capsules 4 mg
Silodosin Capsules (4mg, 8mg) is an ultra-selective alpha-1A adrenergic receptor antagonist on the PMBI formulary. It demonstrates an extraordinarily high alpha-1A to alpha-1B binding affinity ratio (162:1), targeting the lower urinary tract smooth muscle with surgical precision while sparing vascular alpha-1B receptors that regulate arterial blood pressure. This confers excellent cardiovascular safety and minimal postural hypotension. Indicated for the treatment of the signs and symptoms of Benign Prostatic Hyperplasia (BPH) in adult men.
Silodosin Capsules 8 mg
Silodosin Capsules (4mg, 8mg) is an ultra-selective alpha-1A adrenergic receptor antagonist on the PMBI formulary. It demonstrates an extraordinarily high alpha-1A to alpha-1B binding affinity ratio (162:1), targeting the lower urinary tract smooth muscle with surgical precision while sparing vascular alpha-1B receptors that regulate arterial blood pressure. This confers excellent cardiovascular safety and minimal postural hypotension. Indicated for the treatment of the signs and symptoms of Benign Prostatic Hyperplasia (BPH) in adult men.
Silodosin 4mg + Dutasteride 0.5mg Capsules
Silodosin (4mg/8mg) and Dutasteride (0.5mg) Capsules is an advanced fixed-dose combination for Benign Prostatic Hyperplasia (BPH). Silodosin is an ultra-selective alpha-1A adrenergic receptor antagonist (>160-fold selectivity over alpha-1B receptors), providing targeted bladder neck and prostatic relaxation with minimal vascular hypotensive effects. Dutasteride blocks both 5-alpha reductase isoforms, permanently lowering circulating and intraprostatic DHT to shrink prostate gland tissue. Indicated for treatment of moderate-to-severe LUTS associated with prostatic enlargement.
Silodosin 8mg + Dutasteride 0.5mg Capsules
Silodosin (4mg/8mg) and Dutasteride (0.5mg) Capsules is an advanced fixed-dose combination for Benign Prostatic Hyperplasia (BPH). Silodosin is an ultra-selective alpha-1A adrenergic receptor antagonist (>160-fold selectivity over alpha-1B receptors), providing targeted bladder neck and prostatic relaxation with minimal vascular hypotensive effects. Dutasteride blocks both 5-alpha reductase isoforms, permanently lowering circulating and intraprostatic DHT to shrink prostate gland tissue. Indicated for treatment of moderate-to-severe LUTS associated with prostatic enlargement.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Silodosin.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Silodosin Capsules 4 mg | 10's | ₹46.88 | SILODAL | ₹202.56 | 77% Save |
| Silodosin Capsules 8 mg | 10's | ₹77.34 | SILODAL | ₹287.10 | 73% Save |
| Silodosin 4mg + Dutasteride 0.5mg Capsules | 10's | ₹93.75 | PROSTAGARD | ₹169.77 | 45% Save |
| Silodosin 8mg + Dutasteride 0.5mg Capsules | 10's | ₹144.38 | SILODAL, PROSTAGARD D, SILOFAST, SILDOEASE, SILIOSTRU | ₹310.12 | 53% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Silodosin generics.