Selexipag
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Cardiac & Hypertension treatment.
🧴 Clinical Application
Take orally twice daily (morning and evening) with food to improve tolerability, with water. Titrate dose gradually up to the highest tolerated individual maintenance dose as instructed by your PAH specialist.
⚠️ Side Effects
Common: Headache, diarrhea, jaw pain, nausea, myalgia, vomiting, pain in extremity, flushing, arthralgia. Rare/Severe: Severe hypotension, anemia, pulmonary edema in pulmonary veno-occlusive disease, and hyperthyroidism.
🛡️ Safety Warnings
High incidence of prostacyclin-related vasodilatory adverse effects (jaw pain, headache, diarrhea) during dose titration; manage with symptom relief rather than abrupt discontinuation. Contraindicated in severe coronary artery disease and decompensated heart failure.
Jan Aushadhi Products containing Selexipag
Found 2 generic formulation(s) containing this active ingredient.
Selexipag Tablets 200mcg
Selexipag is an orally active, selective, non-prostanoid prostacyclin (IP) receptor agonist on the WHO Model List of Essential Medicines. It is hydrolyzed by carboxylesterase 1 into an active metabolite with 37-fold higher potency. Stimulation of the IP receptor activates adenylyl cyclase, elevating intracellular cyclic AMP and producing potent pulmonary vasodilation and anti-proliferative effects. Indicated for the long-term treatment of Pulmonary Arterial Hypertension (PAH, WHO Group 1) to delay disease progression and reduce hospitalization.
Selexipag Tablets 400mcg
Selexipag is an orally active, selective, non-prostanoid prostacyclin (IP) receptor agonist on the WHO Model List of Essential Medicines. It is hydrolyzed by carboxylesterase 1 into an active metabolite with 37-fold higher potency. Stimulation of the IP receptor activates adenylyl cyclase, elevating intracellular cyclic AMP and producing potent pulmonary vasodilation and anti-proliferative effects. Indicated for the long-term treatment of Pulmonary Arterial Hypertension (PAH, WHO Group 1) to delay disease progression and reduce hospitalization.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Selexipag.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Selexipag Tablets 200mcg | 10's | ₹393.75 | SELEPEG | ₹42.88 | N/A |
| Selexipag Tablets 400mcg | 10's | Under Process | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Selexipag generics.