Ranolazine
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Cardiac & Hypertension treatment.
🧴 Clinical Application
Swallow extended-release tablets whole with water, twice daily, with or without meals. Do not crush, break, or chew tablets. Complete regular medical evaluations.
⚠️ Side Effects
Common: Dizziness, headache, constipation, nausea, asthenia. Rare/Severe: Dose-dependent QTc interval prolongation, torsades de pointes, syncope, and acute renal failure in severe renal impairment.
🛡️ Safety Warnings
Prolongs the QTc interval; caution in patients with congenital long QT syndrome or taking other QTc-prolonging drugs. Contraindicated in clinically significant hepatic cirrhosis and concomitant administration of strong CYP3A4 inhibitors (ketoconazole, clarithromycin) or inducers (rifampicin, carbamazepine).
Jan Aushadhi Products containing Ranolazine
Found 2 generic formulation(s) containing this active ingredient.
Ranolazine Extended Release Tablets 500mg
Ranolazine is a piperazine derivative late sodium current (I_Na,late) inhibitor. In ischemic cardiomyocytes, pathological enhancement of late sodium influx leads to intracellular sodium accumulation, triggering the reverse mode of the Na+/Ca2+ exchanger and causing toxic intracellular calcium overload, diastolic left ventricular wall tension, and microvascular compression. Ranolazine selectively inhibits I_Na,late, attenuating calcium overload and improving diastolic myocardial perfusion without lowering heart rate or blood pressure. Indicated for the treatment of chronic stable angina pectoris.
Ranolazine Extended Release Tablets 1000mg
Ranolazine is a piperazine derivative late sodium current (I_Na,late) inhibitor. In ischemic cardiomyocytes, pathological enhancement of late sodium influx leads to intracellular sodium accumulation, triggering the reverse mode of the Na+/Ca2+ exchanger and causing toxic intracellular calcium overload, diastolic left ventricular wall tension, and microvascular compression. Ranolazine selectively inhibits I_Na,late, attenuating calcium overload and improving diastolic myocardial perfusion without lowering heart rate or blood pressure. Indicated for the treatment of chronic stable angina pectoris.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Ranolazine.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Ranolazine Extended Release Tablets 500mg | 10's | ₹56.72 | RANOZEX, RANOLAZ, RANX, RANOGARD, RANCAD | ₹171.38 | 67% Save |
| Ranolazine Extended Release Tablets 1000mg | 10's | ₹70.31 | RANCV | ₹178.88 | 61% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Ranolazine generics.