Prucalopride
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Gastrointestinal & Digestion treatment.
🧴 Clinical Application
Take orally once daily, 2 mg once daily (1 mg once daily in elderly >65 years or patients with renal impairment CrCl < 50 mL/min) with or without food, with a glass of water. Swallow whole. If no improvement is observed after 4 weeks of therapy, re-evaluate treatment benefit.
⚠️ Side Effects
Common: Headache, nausea, abdominal pain, diarrhea, dizziness, fatigue (most prominent on day 1 and typically resolve within a few days). Rare/Severe: Palpitations, rectal bleeding, and severe depression/suicidal ideation (rare reported associations).
🛡️ Safety Warnings
Prescription prokinetic. Unlike cisapride or tegaserod, prucalopride does NOT block HERG channels and does not induce QT prolongation or ischemic events. Contraindicated in renal failure requiring dialysis, intestinal perforation, obstructive ileus, and severe inflammatory bowel disease (Crohn's, ulcerative colitis).
Jan Aushadhi Products containing Prucalopride
Found 2 generic formulation(s) containing this active ingredient.
Prucalopride Tablet 2 mg
Prucalopride Tablets (1mg, 2mg) is a first-in-class, high-affinity, selective serotonin 5-HT4 receptor agonist prokinetic. It stimulates 5-HT4 receptors on colonic intramural neurons, triggering giant migrating contractions that accelerate colonic transit without interacting with dopamine D2 receptors, 5-HT1, 5-HT2, or cardiac HERG potassium channels. Indicated for symptomatic treatment of chronic idiopathic constipation in adults in whom conventional laxatives fail to provide adequate relief.
Prucalopride Tablets 1mg
Prucalopride Tablets (1mg, 2mg) is a first-in-class, high-affinity, selective serotonin 5-HT4 receptor agonist prokinetic. It stimulates 5-HT4 receptors on colonic intramural neurons, triggering giant migrating contractions that accelerate colonic transit without interacting with dopamine D2 receptors, 5-HT1, 5-HT2, or cardiac HERG potassium channels. Indicated for symptomatic treatment of chronic idiopathic constipation in adults in whom conventional laxatives fail to provide adequate relief.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Prucalopride.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Prucalopride Tablet 2 mg | 10's | ₹112.50 | PRUCALOPRIDE, PRUVICT, PRUEASE, PRUSENT, PRUWEL | ₹439.12 | 74% Save |
| Prucalopride Tablets 1mg | 10's | ₹84.38 | PRUVICT, PRUEASE, PRUCOLPRIDE, PRULOFORD, PRUSENT | ₹207.71 | 59% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Prucalopride generics.