Memantine
Active pharmaceutical substance formulated in Jan Aushadhi generic products for CNS, Nerve & Mental Health treatment.
🧴 Clinical Application
Take orally once daily with water, with or without food. Titrate dose gradually in weekly increments to the target maintenance dose (20 mg/day). Follow doctor's schedule.
⚠️ Side Effects
Common: Dizziness, headache, confusion, constipation, somnolence, hypertension, coughing. Rare/Severe: Seizures, heart failure, psychosis, pancreatitis, and acute renal failure.
🛡️ Safety Warnings
Caution in patients with severe renal impairment (dosage reduction required if CrCl < 30 mL/min) and history of seizure disorders. Alkalinizing agents (sodium bicarbonate, carbonic anhydrase inhibitors) reduce renal clearance of memantine, increasing toxicity risk.
Jan Aushadhi Products containing Memantine
Found 3 generic formulation(s) containing this active ingredient.
Memantine Hydrochloride Tablets 10mg
Memantine Hydrochloride is an uncompetitive, low-to-moderate affinity, voltage-dependent N-methyl-D-aspartate (NMDA) receptor antagonist. Pathological chronic exposure to high glutamate concentrations produces excitotoxic neuronal death in Alzheimer's disease; memantine blocks pathological tonic glutamate influx through NMDA channels while preserving physiological phasic neurotransmission necessary for learning and memory. Indicated for moderate-to-severe dementia of the Alzheimer's type.
Donepezil 5mg + Memantine 5mg Tablets
Donepezil and Memantine is a complementary dual-mechanism formulation for moderate-to-severe dementia. Donepezil, a reversible piperidine acetylcholinesterase inhibitor, increases acetylcholine concentrations at cerebral synapses, while memantine, an uncompetitive NMDA receptor antagonist, protects cholinergic neurons against pathological chronic glutamate-mediated excitotoxicity. Indicated for moderate-to-severe dementia of the Alzheimer's type.
Donepezil 5mg + Memantine 10mg Tablets
Donepezil and Memantine is a complementary dual-mechanism formulation for moderate-to-severe dementia. Donepezil, a reversible piperidine acetylcholinesterase inhibitor, increases acetylcholine concentrations at cerebral synapses, while memantine, an uncompetitive NMDA receptor antagonist, protects cholinergic neurons against pathological chronic glutamate-mediated excitotoxicity. Indicated for moderate-to-severe dementia of the Alzheimer's type.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Memantine.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Memantine Hydrochloride Tablets 10mg | 10's | ₹23.44 | ADMENTA, NEMDAA, MENTATIME, LARENTINE | ₹196.38 | 88% Save |
| Donepezil 5mg + Memantine 5mg Tablets | 10's | ₹18.75 | DONEP, DONAMEM, DONEPAZE, ALZIL, ARICEP | ₹186.38 | 90% Save |
| Donepezil 5mg + Memantine 10mg Tablets | 10's | ₹23.44 | DONEP, DONAMEM | ₹269.77 | 91% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Memantine generics.