Levosulpiride

Pantoprazole (40mg enteric-coated) and Levosulpiride (75mg sustained-release) is a potent combination of a proton pump inhibitor and a prokinetic benzamide. Pantoprazole profoundly suppresses gastric acid synthesis by blocking H+/K+-ATPase pumps. Levosulpiride is the levorotatory enantiomer of sulpiride that selectively antagonizes dopamine D2 receptors in the enteric nervous system and acts as an agonist at 5-HT4 receptors, accelerating gastric and gallbladder emptying and improving antropyloric coordination. Indicated for severe GERD refractory to conventional prokinetics, diabetic gastroparesis, and functional dyspepsia with prominent postprandial distress syndrome.

Esomeprazole (40mg enteric-coated) and Levosulpiride (75mg sustained-release) combines an S-isomer proton pump inhibitor with a central/peripheral prokinetic benzamide. Esomeprazole exerts long-lasting suppression of basal and meal-stimulated gastric acid secretion. Levosulpiride selectively blocks enteric D2 receptors and stimulates 5-HT4 receptors, dramatically improving gastric accommodation and antral motility. Indicated for severe GERD, refractory non-ulcer dyspepsia, and gastroparesis.

Levosulpiride Tablets (25mg, 50mg, 75mg) is the pure levorotatory (S)-enantiomer of sulpiride, acting as a selective dopamine D2 receptor antagonist and 5-HT4 receptor agonist. In the gastrointestinal tract, it increases lower esophageal sphincter tone and accelerates gastric emptying; centrally, it modulates mood and relieves visceral pain. Indicated for functional dyspepsia (postprandial distress syndrome), diabetic gastroparesis, and gastroesophageal reflux disease unresponsive to standard prokinetics.

Levosulpiride Tablets (25mg, 50mg, 75mg) is the pure levorotatory (S)-enantiomer of sulpiride, acting as a selective dopamine D2 receptor antagonist and 5-HT4 receptor agonist. In the gastrointestinal tract, it increases lower esophageal sphincter tone and accelerates gastric emptying; centrally, it modulates mood and relieves visceral pain. Indicated for functional dyspepsia (postprandial distress syndrome), diabetic gastroparesis, and gastroesophageal reflux disease unresponsive to standard prokinetics.

Levosulpiride Tablets (25mg, 50mg, 75mg) is the pure levorotatory (S)-enantiomer of sulpiride, acting as a selective dopamine D2 receptor antagonist and 5-HT4 receptor agonist. In the gastrointestinal tract, it increases lower esophageal sphincter tone and accelerates gastric emptying; centrally, it modulates mood and relieves visceral pain. Indicated for functional dyspepsia (postprandial distress syndrome), diabetic gastroparesis, and gastroesophageal reflux disease unresponsive to standard prokinetics.