Ibrutinib
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Take orally once daily (420 mg for CLL, 560 mg for MCL) with a full glass of water at approximately the same time each day, with or without food. Swallow capsules whole; do not open or dissolve. Transient redistribution lymphocytosis is expected during initial weeks and does not signify disease progression.
⚠️ Side Effects
Common: Diarrhea, fatigue, musculoskeletal pain, bruising/ecchymosis, upper respiratory infection, nausea, rash. Rare/Severe: Atrial fibrillation/flutter (up to 6-9%), ventricular arrhythmias, severe bleeding/major hemorrhage (inhibits collagen-induced platelet aggregation), hypertension, and opportunistic infections.
🛡️ Safety Warnings
Bleeding risk: avoid concomitant warfarin; withhold ibrutinib 3 to 7 days before and after surgical procedures. Monitor for cardiac arrhythmias (atrial fibrillation). Substrate of CYP3A4; avoid grapefruits, Seville oranges, and strong CYP3A4 inhibitors.
Jan Aushadhi Products containing Ibrutinib
Found 1 generic formulation(s) containing this active ingredient.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Ibrutinib.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Ibrutinib Capsule 140 Mg | 30's in Bottle | Under Process | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
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