⚕ Rx (Prescription Required)Oncology & Critical CareTargeted Therapies & Kinase Inhibitors

Ibrutinib

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.

🧴 Clinical Application

Take orally once daily (420 mg for CLL, 560 mg for MCL) with a full glass of water at approximately the same time each day, with or without food. Swallow capsules whole; do not open or dissolve. Transient redistribution lymphocytosis is expected during initial weeks and does not signify disease progression.

⚠️ Side Effects

Common: Diarrhea, fatigue, musculoskeletal pain, bruising/ecchymosis, upper respiratory infection, nausea, rash. Rare/Severe: Atrial fibrillation/flutter (up to 6-9%), ventricular arrhythmias, severe bleeding/major hemorrhage (inhibits collagen-induced platelet aggregation), hypertension, and opportunistic infections.

🛡️ Safety Warnings

Bleeding risk: avoid concomitant warfarin; withhold ibrutinib 3 to 7 days before and after surgical procedures. Monitor for cardiac arrhythmias (atrial fibrillation). Substrate of CYP3A4; avoid grapefruits, Seville oranges, and strong CYP3A4 inhibitors.

Jan Aushadhi Products containing Ibrutinib

Found 1 generic formulation(s) containing this active ingredient.

⚕ Rx OnlyTargeted Therapies & Kinase Inhibitors

Ibrutinib Capsule 140 Mg

Capsules
30's in Bottle

Ibrutinib Capsules (140mg) is a first-in-class oral irreversible inhibitor of Bruton's Tyrosine Kinase (BTK) on the WHO Model List of Essential Medicines. It forms a covalent bond with cysteine 481 in the BTK active site, permanently disabling B-cell antigen receptor (BCR) signaling and halting malignant B-cell proliferation, survival, and homing to lymphatic niches. Indicated for Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL), Waldenstrom's Macroglobulinemia, and chronic Graft-versus-Host Disease (cGVHD).

Brand Equivalents & Price Comparison

Compare Jan Aushadhi generic prices against popular commercial brands for Ibrutinib.

Generic FormulationPack SizeJan Aushadhi PriceCommercial Brand EquivalentsAvg. Commercial PriceSavings
Ibrutinib Capsule 140 Mg30's in BottleUnder ProcessN/AN/AN/A

Frequently Asked Questions (FAQ)

Get answers to common queries about Ibrutinib generics.

How many Jan Aushadhi products contain Ibrutinib?+
This directory currently lists 1 Jan Aushadhi generic product(s) containing Ibrutinib as an active pharmaceutical ingredient (API). The count reflects the July 2026 PMBI catalog snapshot.
Does Ibrutinib require a prescription at Jan Aushadhi Kendras?+
Yes. Ibrutinib is classified as a prescription-required (Rx) ingredient under applicable Indian drug schedules. You must present a valid prescription from a registered medical practitioner to obtain it at a Jan Aushadhi Kendra.
What is the lowest listed price for Ibrutinib at Jan Aushadhi?+
Price data for Ibrutinib formulations is currently listed as "under process" in the July 2026 PMBI catalog. Visit a Jan Aushadhi Kendra and quote the product drug code for the applicable MRP.
Are Jan Aushadhi Ibrutinib products clinically equivalent to branded versions?+
Jan Aushadhi generics contain the same declared active pharmaceutical ingredient (Ibrutinib) at the same concentration as branded counterparts and must meet CDSCO quality standards. However, inactive excipients, release mechanisms, and manufacturing processes can differ between manufacturers. Never switch a prescribed medicine without consulting your doctor.
Find a Jan Aushadhi Kendra Near You
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