Dydrogesterone

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Women's Health & Hormones treatment.

🧴 Clinical Application

Take orally 10 mg one to three times daily with water, with or without food: For threatened abortion: 40 mg stat, followed by 10 mg every 8 hours until symptoms remit, then gradually tapered. For luteal phase support in IVF: 10 mg three times daily (30 mg/day) starting from oocyte retrieval until 12 weeks of pregnancy. For endometriosis/dysmenorrhea: 10 mg two to three times daily from Day 5 to Day 25 of the menstrual cycle.

⚠️ Side Effects

Common: Headache, nausea, dizziness, breast pain/tenderness, breakthrough bleeding/spotting, and abdominal pain. Rare/Severe: Hepatic dysfunction, angioedema, hemolytic anemia, and depression. Unlike older progestogens, it does not cause virilization, fluid retention, or androgenic acne.

🛡️ Safety Warnings

Contraindicated in undiagnosed abnormal vaginal bleeding, active venous thromboembolism, severe hepatic impairment, and known progestogen-dependent neoplasms (meningioma). High safety profile in pregnancy established across multi-center clinical trials.