Doxorubicin
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Administer intravenously by slow IV push (over 3 to 10 minutes) or short IV infusion into the tubing of a freely flowing IV infusion of 0.9% NaCl or 5% Dextrose. Ensure secure vascular access; NEVER administer IM or subcutaneously. Cumulative lifetime dose must NOT exceed 450 to 550 mg/m² to prevent irreversible congestive heart failure.
⚠️ Side Effects
Common: Alopecia (universal, reversible), acute nausea and vomiting, dose-limiting myelosuppression, stomatitis/mucositis, harmless reddish-orange discoloration of urine for 1-2 days post-infusion. Rare/Severe: Irreversible dilated cardiomyopathy / congestive heart failure, severe local extravasation necrosis, and radiation recall reaction.
🛡️ Safety Warnings
Black Box Warning: Cumulative lifetime dose-dependent cardiotoxicity; perform baseline and periodic echocardiography or MUGA scans (LVEF monitoring). Black Box Warning: Potent vesicant; extravasation causes deep tissue ulceration and necrosis (dexrazoxane is the specific antidote). Black Box Warning: Severe myelosuppression.
Jan Aushadhi Products containing Doxorubicin
Found 1 generic formulation(s) containing this active ingredient.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Doxorubicin.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Doxorubicin Injection 50mg (2mg per ml) | Vial | ₹281.25 | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
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