Docetaxel
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Administer intravenously only over 1 hour diluted in 0.9% NaCl or 5% Dextrose. MANDATORY PREMEDICATION: Dexamethasone 8 mg orally twice daily for 3 consecutive days, starting the day prior to docetaxel administration, to mitigate severe fluid retention and hypersensitivity reactions.
⚠️ Side Effects
Common: Complete alopecia, neutropenia (nadir day 7), fatigue, asthenia, stomatitis, onycholysis (nail dystrophy and hyperpigmentation). Rare/Severe: Severe fluid retention / third-spacing (pleural effusion, ascites, generalized peripheral edema), fatal enterocolitis/neutropenic typhlitis, and severe hypersensitivity.
🛡️ Safety Warnings
Black Box Warning: Treatment-related mortality in patients with abnormal liver function; contraindicated in patients with bilirubin > ULN or AST/ALT > 1.5× ULN with alkaline phosphatase > 2.5× ULN. Black Box Warning: Severe neutropenia. Black Box Warning: Severe fluid retention; mandatory 3-day oral corticosteroid premedication is essential.
Jan Aushadhi Products containing Docetaxel
Found 2 generic formulation(s) containing this active ingredient.
Docetaxel Injection 80 mg
Docetaxel Injection (80mg, 120mg) is a semi-synthetic taxane antineoplastic on the WHO Model List of Essential Medicines. It binds to free tubulin and stabilizes microtubule bundles, inhibiting mitotic spindle dissolution with approximately double the tubulin-binding affinity of paclitaxel. Indicated for locally advanced or metastatic breast cancer, non-small cell lung cancer, hormone-refractory metastatic prostate cancer (with prednisone), gastric adenocarcinoma, and squamous cell carcinoma of the head and neck.
Docetaxel Injection 120 mg
Docetaxel Injection (80mg, 120mg) is a semi-synthetic taxane antineoplastic on the WHO Model List of Essential Medicines. It binds to free tubulin and stabilizes microtubule bundles, inhibiting mitotic spindle dissolution with approximately double the tubulin-binding affinity of paclitaxel. Indicated for locally advanced or metastatic breast cancer, non-small cell lung cancer, hormone-refractory metastatic prostate cancer (with prednisone), gastric adenocarcinoma, and squamous cell carcinoma of the head and neck.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Docetaxel.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Docetaxel Injection 80 mg | VIAL | ₹1687.50 | ADOXI, ZYTAX, DOCETERE, DOCET, Docetere | ₹3790.17 | 55% Save |
| Docetaxel Injection 120 mg | VIAL | ₹2531.25 | DOCETERE, DAXOTEL, TAXOCARE, DOCET, DOCETERO | ₹5796.25 | 56% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Docetaxel generics.