Clozapine
Active pharmaceutical substance formulated in Jan Aushadhi generic products for CNS, Nerve & Mental Health treatment.
🧴 Clinical Application
Take orally with water, divided throughout the day or at bedtime. Mandatory absolute neutrophil count (ANC) registry monitoring is required prior to dispensing (weekly for first 6 months, then biweekly for 6 months, then monthly). Titrate very slowly.
⚠️ Side Effects
Common: Hypersalivation (sialorrhea, especially nocturnal), sedation, severe weight gain, constipation, tachycardia, dizziness, fever. Rare/Severe: Boxed warnings: Severe neutropenia/agranulocytosis, myocarditis and cardiomyopathy, fatal gastrointestinal hypomotility/ileus, seizures (dose-dependent), and orthostatic syncope.
🛡️ Safety Warnings
Five Black Box Warnings: (1) Severe agranulocytosis (mandatory regular ANC blood monitoring); (2) Fatal myocarditis and cardiomyopathy; (3) Life-threatening gastrointestinal hypomotility/fecal impaction; (4) Dose-dependent seizures; (5) Mortality in dementia psychosis. Discontinue immediately if myocarditis symptoms (chest pain, tachycardia, fever) or severe neutropenia develop.
Jan Aushadhi Products containing Clozapine
Found 4 generic formulation(s) containing this active ingredient.
Clozapine Tablets 25 mg
Clozapine is a dibenzodiazepine prototype atypical antipsychotic on the WHO Model List of Essential Medicines. It possesses weak affinity for dopamine D2 receptors and potent blockade of D4, 5-HT2A, alpha-1, and muscarinic receptors. Demonstrates unique superiority in reducing suicidal behavior and treating refractory psychosis without producing extrapyramidal symptoms or tardive dyskinesia. Strictly reserved for treatment-resistant schizophrenia and reducing suicidal behavior in schizophrenia or schizoaffective disorder.
Clozapine Tablets 50 mg
Clozapine is a dibenzodiazepine prototype atypical antipsychotic on the WHO Model List of Essential Medicines. It possesses weak affinity for dopamine D2 receptors and potent blockade of D4, 5-HT2A, alpha-1, and muscarinic receptors. Demonstrates unique superiority in reducing suicidal behavior and treating refractory psychosis without producing extrapyramidal symptoms or tardive dyskinesia. Strictly reserved for treatment-resistant schizophrenia and reducing suicidal behavior in schizophrenia or schizoaffective disorder.
Clozapine Tablets 100 mg
Clozapine is a dibenzodiazepine prototype atypical antipsychotic on the WHO Model List of Essential Medicines. It possesses weak affinity for dopamine D2 receptors and potent blockade of D4, 5-HT2A, alpha-1, and muscarinic receptors. Demonstrates unique superiority in reducing suicidal behavior and treating refractory psychosis without producing extrapyramidal symptoms or tardive dyskinesia. Strictly reserved for treatment-resistant schizophrenia and reducing suicidal behavior in schizophrenia or schizoaffective disorder.
Clozapine tablets 200mg
Clozapine is a dibenzodiazepine prototype atypical antipsychotic on the WHO Model List of Essential Medicines. It possesses weak affinity for dopamine D2 receptors and potent blockade of D4, 5-HT2A, alpha-1, and muscarinic receptors. Demonstrates unique superiority in reducing suicidal behavior and treating refractory psychosis without producing extrapyramidal symptoms or tardive dyskinesia. Strictly reserved for treatment-resistant schizophrenia and reducing suicidal behavior in schizophrenia or schizoaffective disorder.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Clozapine.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Clozapine Tablets 25 mg | 10's | ₹14.06 | Skizoril, Lozapin, Alkepin Odt, Sizep | ₹28.02 | 50% Save |
| Clozapine Tablets 50 mg | 10's | ₹23.44 | SOLOQUIN | ₹27.87 | 16% Save |
| Clozapine Tablets 100 mg | 10's | ₹37.50 | Sizopin, Skizoril, Lozapin, Alkepin Odt, Sizep | ₹86.28 | 57% Save |
| Clozapine tablets 200mg | 10's | ₹75.00 | CIZASPA | ₹207.02 | 64% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Clozapine generics.