Carboprost

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Women's Health & Hormones treatment.

🧴 Clinical Application

For Deep Intramuscular (IM) injection ONLY: 125 mcg to 250 mcg deep IM into the gluteal muscle or anterolateral thigh, administered by an obstetrician. In severe PPH, may repeat at 15 to 90 minute intervals as clinically necessary (maximum cumulative dose: 2 mg). NEVER administer intravenously (severe risk of bronchospasm, hypertension, and pulmonary edema).

⚠️ Side Effects

Common: Diarrhea (in >60% of patients due to intestinal smooth muscle stimulation), vomiting, nausea, flushing, transient pyrexia/chills, shivering, and headache. Rare/Severe: Severe acute bronchospasm, acute hypertension, pulmonary edema, cardiac arrest, and uterine rupture.

🛡️ Safety Warnings

Absolute Contraindication: Acute active pelvic inflammatory disease, active severe pulmonary/cardiac disease, and severe asthma (potent bronchoconstrictor). Use with extreme caution in patients with hepatic or renal impairment, history of bronchial asthma, epilepsy, or cardiovascular disease.