Alteplase (rt-PA)
Recombinant human tissue-type plasminogen activator (rt-PA) that catalyzes conversion of plasminogen to plasmin, dissolving intravascular fibrin clots.
🧴 Clinical Application
Administered intravenously in hospital emergency/ICU settings for acute ischemic stroke (within 4.5 hours) or acute myocardial infarction.
⚠️ Side Effects
Hemorrhage (internal or superficial), intracranial hemorrhage, hematoma.
🛡️ Safety Warnings
Critical high-risk thrombolytic. Strict protocol and exclusion criteria apply. Hospital use only.
Jan Aushadhi Products containing Alteplase (rt-PA)
Found 2 generic formulation(s) containing this active ingredient.
Alteplase (Recombinant Tissue Plasminogen Activator) 20mg Injection
Recombinant Human Tissue-type Plasminogen Activator (rt-PA / Alteplase) is a fibrin-specific thrombolytic biological enzyme on the WHO Model List of Essential Medicines. It binds selectively to fibrin in a thrombus and converts trapped plasminogen into active plasmin, which cleaves fibrin matrices and dissolves the occlusive blood clot, restoring organ perfusion. Indicated for acute ischemic stroke (within 4.5 hours of symptom onset), acute ST-elevation myocardial infarction (STEMI), and massive acute pulmonary embolism with hemodynamic instability.
Alteplase (Recombinant Tissue Plasminogen Activator) 50mg Injection
Recombinant Human Tissue-type Plasminogen Activator (rt-PA / Alteplase) is a fibrin-specific thrombolytic biological enzyme on the WHO Model List of Essential Medicines. It binds selectively to fibrin in a thrombus and converts trapped plasminogen into active plasmin, which cleaves fibrin matrices and dissolves the occlusive blood clot, restoring organ perfusion. Indicated for acute ischemic stroke (within 4.5 hours of symptom onset), acute ST-elevation myocardial infarction (STEMI), and massive acute pulmonary embolism with hemodynamic instability.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Alteplase (rt-PA).
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Alteplase (Recombinant Tissue Plasminogen Activator) 20mg Injection | Vial with WFI and Transfer canula in Mono Carton | Under Process | N/A | N/A | N/A |
| Alteplase (Recombinant Tissue Plasminogen Activator) 50mg Injection | Vial with WFI and Transfer canula in Mono Carton | Under Process | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
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