TabletsClinical Overview
Lorazepam is a high-potency, intermediate-acting 3-hydroxy benzodiazepine on the WHO Model List of Essential Medicines. It enhances GABA-mediated synaptic inhibition by binding to GABAA receptors. Because it undergoes direct hepatic glucuronidation to inactive metabolites without intermediate oxidative CYP450 steps, it is the benzodiazepine of choice in patients with hepatic impairment and the elderly. Indicated for short-term management of severe anxiety, insomnia associated with anxiety, acute status epilepticus, and pre-anesthetic sedation.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with water, with or without food. For anxiety, divide into two to three doses daily; for insomnia, take as a single bedtime dose. Strictly avoid sudden discontinuation; taper gradually over several weeks.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Sedation, dizziness, weakness, unsteadiness, confusion, memory impairment. Rare/Severe: Boxed warning: Respiratory depression, addiction/physical dependence, severe withdrawal seizures, and paradoxical hostility.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Concomitant use with opioids may result in profound sedation, respiratory depression, coma, and death. High dependence potential. Contraindicated in acute narrow-angle glaucoma and severe respiratory insufficiency. Avoid alcohol.
Schedule H1 (Prescription Required - Habit Forming Warning)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Lorazepam Tablets 2mg
Lorazepam is a high-potency, intermediate-acting 3-hydroxy benzodiazepine on the WHO Model List of Essential Medicines. It enhances GABA-mediated synaptic inhibition by binding to GABAA receptors. Because it undergoes direct hepatic glucuronidation to inactive metabolites without intermediate oxidative CYP450 steps, it is the benzodiazepine of choice in patients with hepatic impairment and the elderly. Indicated for short-term management of severe anxiety, insomnia associated with anxiety, acute status epilepticus, and pre-anesthetic sedation.
Lorazepam Tablets 3mg
Lorazepam is a high-potency, intermediate-acting 3-hydroxy benzodiazepine on the WHO Model List of Essential Medicines. It enhances GABA-mediated synaptic inhibition by binding to GABAA receptors. Because it undergoes direct hepatic glucuronidation to inactive metabolites without intermediate oxidative CYP450 steps, it is the benzodiazepine of choice in patients with hepatic impairment and the elderly. Indicated for short-term management of severe anxiety, insomnia associated with anxiety, acute status epilepticus, and pre-anesthetic sedation.