InjectionClinical Overview
Gentamicin Sulphate is a bactericidal aminoglycoside antibiotic produced by Micromonospora purpurea. It acts by binding to the 30S bacterial ribosome, disrupting protein elongation and destabilizing bacterial cell membranes. Used in the management of severe systemic infections, including sepsis, complicated intra-abdominal infections, pyelonephritis, endocarditis (in synergy with beta-lactams), and pelvic inflammatory disease caused by susceptible aerobic Gram-negative pathogens.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered solely by trained medical personnel via deep intramuscular injection or slow intravenous infusion diluted in compatible IV fluids over 30-120 minutes. Regular therapeutic drug monitoring (peak and trough blood levels) is recommended for extended courses.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Injection site discomfort, mild nausea. Rare/Severe: Irreversible ototoxicity (tinnitus, high-frequency hearing loss, ataxia, vertigo), nephrotoxicity (proteinuria, rising serum creatinine, renal failure), and neuromuscular blockade.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in patients with severe hypersensitivity to aminoglycosides. Exercise extreme caution in patients with renal impairment, myasthenia gravis, or parkinsonism. Ensure continuous hydration. Concomitant use with ethacrynic acid, furosemide, or other aminoglycosides is strongly discouraged.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Beclomethasone Dipropionate 0.025%, Clotrimazole 1% and Gentamicin Sulphate 0.1% Cream
Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.
Gentamicin Eye Drops 0.3% w/v
Gentamicin Eye Drops 0.3% w/v is an evidence-based ophthalmic/otic formulation. It acts by delivering targeted active therapeutic substances to external ocular or auditory tissues to control infection, relieve inflammation, or restore tissue homeostasis.
Betamethasone Valerate 0.12%, Gentamicin 0.1% and Miconazole Nitrate 2% Cream
Betamethasone Valerate / Dipropionate is a potent topical corticosteroid on the WHO Model List of Essential Medicines. It suppresses cutaneous inflammatory edema, erythema, and pruritus in eczema, psoriasis, and severe contact dermatitis. Often formulated in combination with Fusidic Acid, Gentamicin, or Miconazole to treat secondarily infected dermatoses.
Clobetasol Propionate 0.05% and Gentamicin 0.1% Cream
Clobetasol Propionate (0.05%) combined with antibacterial (Gentamicin/Neomycin) and/or antifungal (Miconazole) agents. Delivers rapid anti-inflammatory and anti-pruritic relief while providing broad-spectrum coverage against secondary bacterial and candidal/dermatophyte infections in steroid-responsive dermatoses. Indicated for infected inflammatory dermatoses, infected eczema, and severe intertrigo.