InjectionClinical Overview
Hydrocortisone (Sodium Succinate Injection IP 100mg) is the bioidentical synthetic equivalent of endogenous human cortisol on the WHO Model List of Essential Medicines. It possesses balanced 1:1 glucocorticoid and mineralocorticoid activity, providing vital metabolic regulation, vascular tone maintenance, and immune stabilization. Indicated for acute adrenal crisis / Addisonian crisis (emergency IV therapy), chronic primary or secondary adrenocortical insufficiency (oral physiological replacement), congenital adrenal hyperplasia (CAH), severe septic shock unresponsive to vasopressors, and life-threatening anaphylaxis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
For Intravenous (IV) or Intramuscular (IM) injection: In acute adrenal crisis: 100 mg IV stat bolus over 3-5 minutes, followed by 100 mg IV infusion every 6 to 8 hours diluted in 5% Dextrose in Normal Saline to correct hypoglycemia and hyponatremia. Reconstitute with sterile water for injection.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Emergency IV: Rapid administration may cause transient perineal burning/paresthesia, hypokalemia, hypertension, and hypernatremia. Oral physiological replacement: Minimal ADRs at correct replacement doses; overtreatment causes Cushingoid symptoms, osteoporosis, and weight gain.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Failure to increase dose during acute stress, trauma, or infection can lead to fatal Addisonian crisis. Gradual tapering required if withdrawing supratherapeutic doses. Contraindicated in systemic fungal infections (except for emergency replacement). Patients must carry steroid emergency medical alert identification.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.
Lidocaine (3% ), Calcium Dobesilate (0.25% ), Hydrocortisone (0.25% ), Phenylephrine (0.1% ), Zinc Oxide (5% ), Troxerutin (2% ) Cream
Hydrocortisone Acetate (1% w/w) is a low-potency (Class VII) topical corticosteroid on the WHO Model List of Essential Medicines. It represents the safest topical steroid for sensitive skin areas (face, intertriginous skin folds, groin) and pediatric patients, providing anti-inflammatory, anti-pruritic, and mild vasoconstrictive actions with minimal risk of skin thinning or systemic absorption. Indicated for mild eczema, facial dermatitis, intertrigo, insect bites, and anogenital pruritus.
Fusidic Acid 2% and Hydrocortisone Acetate Cream 1%
Hydrocortisone Acetate (1% w/w) is a low-potency (Class VII) topical corticosteroid on the WHO Model List of Essential Medicines. It represents the safest topical steroid for sensitive skin areas (face, intertriginous skin folds, groin) and pediatric patients, providing anti-inflammatory, anti-pruritic, and mild vasoconstrictive actions with minimal risk of skin thinning or systemic absorption. Indicated for mild eczema, facial dermatitis, intertrigo, insect bites, and anogenital pruritus.
Hydrocortisone Acetate Cream 1%
Hydrocortisone Acetate (1% w/w) is a low-potency (Class VII) topical corticosteroid on the WHO Model List of Essential Medicines. It represents the safest topical steroid for sensitive skin areas (face, intertriginous skin folds, groin) and pediatric patients, providing anti-inflammatory, anti-pruritic, and mild vasoconstrictive actions with minimal risk of skin thinning or systemic absorption. Indicated for mild eczema, facial dermatitis, intertrigo, insect bites, and anogenital pruritus.
Hydrocortisone Tablets 10mg
Hydrocortisone (Tablets 5mg/10mg) is the bioidentical synthetic equivalent of endogenous human cortisol on the WHO Model List of Essential Medicines. It possesses balanced 1:1 glucocorticoid and mineralocorticoid activity, providing vital metabolic regulation, vascular tone maintenance, and immune stabilization. Indicated for acute adrenal crisis / Addisonian crisis (emergency IV therapy), chronic primary or secondary adrenocortical insufficiency (oral physiological replacement), congenital adrenal hyperplasia (CAH), severe septic shock unresponsive to vasopressors, and life-threatening anaphylaxis.