TabletsClinical Overview
Beta-adrenergic receptor antagonist (cardioselective beta-1 blocker, non-selective beta blocker, or third-generation vasodilating beta-blocker with alpha-blockade or nitric oxide release) on the WHO Model List of Essential Medicines. It competitively blocks adrenergic stimulation, reducing heart rate, myocardial contractility, cardiac output, and renin release. Indicated for hypertension, stable angina pectoris, heart failure, cardiac arrhythmias, and post-myocardial infarction secondary prevention.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with a glass of water, once or twice daily with or immediately following meals. Swallow extended-release tablets whole; do not crush or chew. Never stop abruptly; taper slowly over 10-14 days.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Bradycardia (slow heart rate), fatigue, dizziness, cold extremities, hypotension, erectile dysfunction, vivid dreams. Rare/Severe: Boxed warning: Abrupt cessation can precipitate severe exacerbation of angina, ventricular arrhythmias, or acute myocardial infarction; heart block, cardiogenic shock, and severe bronchospasm in asthmatics.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Never stop abruptly; sudden discontinuation can precipitate life-threatening rebound tachycardia, severe angina, or fatal myocardial infarction. Contraindicated in sinus bradycardia (< 50 bpm), second- or third-degree AV block, cardiogenic shock, and decompensated heart failure. Caution in bronchial asthma/COPD and diabetes (masks hypoglycemic tachycardia).
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.
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