InjectionClinical Overview
Ceftriaxone Sodium is an essential third-generation parenteral cephalosporin bactericidal antibiotic on the WHO Model List of Essential Medicines. It features an exceptionally long elimination half-life (around 8 hours), permitting once-daily administration. Crosses the blood-brain barrier effectively. Indicated for bacterial meningitis, septicemia, community-acquired pneumonia, typhoid fever, complicated UTIs, gonococcal infections, pelvic inflammatory disease, and pre-operative surgical prophylaxis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered strictly by medical professionals via deep IM injection or slow IV infusion over 30 minutes after reconstitution with sterile diluent. Do not co-administer or mix with calcium-containing intravenous fluids.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Diarrhea, injection pain, thrombophlebitis, rash, eosinophilia, thrombocytosis. Rare/Severe: Ceftriaxone-calcium precipitation in lungs/kidneys, biliary pseudolithiasis, severe anaphylaxis, and agranulocytosis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Absolute contraindication in hyperbilirubinemic neonates and neonates receiving calcium-containing solutions. Contraindicated in cephalosporin allergy. Caution in severe combined renal and hepatic impairment.
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Ceftriaxone 1g + Sulbactam 500mg Injection
Ceftriaxone Sodium and Sulbactam Sodium is a synergistic parenteral bactericidal formulation. Ceftriaxone provides broad-spectrum third-generation cephalosporin bactericidal action with a prolonged half-life, while sulbactam irreversibly inhibits beta-lactamases, overcoming resistance in ESBL-producing enterobacteriaceae and Acinetobacter. Indicated for severe community- and hospital-acquired pneumonia, sepsis, complicated intra-abdominal infections, pyelonephritis, and surgical prophylaxis.
Ceftriaxone 1g + Tazobactam 125mg Injection
Ceftriaxone Sodium and Tazobactam Sodium combines an extended-spectrum third-generation cephalosporin with the potent beta-lactamase inhibitor tazobactam. Tazobactam prevents ceftriaxone hydrolysis by plasmid- and chromosome-mediated beta-lactamases, restoring full bactericidal activity. Indicated for severe polymicrobial infections, meningitis, sepsis, complicated skin/soft tissue infections, and hospital-acquired lower respiratory infections.
Ceftriaxone 250 mg + Sulbactam 125 mg Injection
Ceftriaxone Sodium and Sulbactam Sodium is a synergistic parenteral bactericidal formulation. Ceftriaxone provides broad-spectrum third-generation cephalosporin bactericidal action with a prolonged half-life, while sulbactam irreversibly inhibits beta-lactamases, overcoming resistance in ESBL-producing enterobacteriaceae and Acinetobacter. Indicated for severe community- and hospital-acquired pneumonia, sepsis, complicated intra-abdominal infections, pyelonephritis, and surgical prophylaxis.
Ceftriaxone 500mg + Sulbactam 250mg Injection
Ceftriaxone Sodium and Sulbactam Sodium is a synergistic parenteral bactericidal formulation. Ceftriaxone provides broad-spectrum third-generation cephalosporin bactericidal action with a prolonged half-life, while sulbactam irreversibly inhibits beta-lactamases, overcoming resistance in ESBL-producing enterobacteriaceae and Acinetobacter. Indicated for severe community- and hospital-acquired pneumonia, sepsis, complicated intra-abdominal infections, pyelonephritis, and surgical prophylaxis.