TabletsClinical Overview
Clotrimazole Vaginal Tablet is a broad-spectrum imidazole antifungal agent. It acts by inhibiting fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking the conversion of lanosterol to ergosterol. The resulting depletion of ergosterol and accumulation of toxic methylsterols disrupts fungal cell membrane integrity, resulting in cell lysis of Candida albicans and other Candida species. Indicated for vulvovaginal candidiasis (vaginal yeast infection).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
For vaginal use only; do not swallow. Insert tablet deep into the vagina at bedtime, preferably while lying on your back with knees bent, using the applicator provided or clean fingers. Complete the prescribed course even during menstruation. Avoid sexual intercourse during treatment.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild vaginal burning, stinging, itching, lower abdominal cramps, or vaginal discharge. Rare/Severe: Severe pelvic irritation, contact dermatitis, and allergic reactions.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Not for oral consumption. May damage latex condoms and diaphragms, reducing their contraceptive efficacy and protection against STIs; avoid latex barrier contraceptives during and for 3 days post-treatment. Consult doctor if symptoms persist after completion or recur within two months.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
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Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.
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Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.
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Clotrimazole (1% w/w cream, lotion, or dusting powder) is a versatile broad-spectrum imidazole antifungal on the WHO Model List of Essential Medicines. It inhibits fungal cytochrome P450 14-alpha-demethylase, depleting ergosterol and increasing fungal cell permeability. Dusting powder formulation absorbs excess moisture in intertriginous skin folds, preventing fungal maceration. Indicated for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and prevention of recurrence in sweaty body folds.