Clinical Overview
Cefotaxime Sodium is a third-generation parenteral cephalosporin bactericidal antibiotic. It binds to PBPs to inhibit peptidoglycan synthesis. Features high cerebrospinal fluid (CSF) penetration, making it an essential first-line agent for bacterial meningitis. Also indicated for severe sepsis, bacteremia, peritonitis, complicated urinary tract infections, and lower respiratory infections.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered by a licensed clinician via deep intramuscular injection or slow intravenous injection over 3-5 minutes, or IV infusion over 20-60 minutes after reconstitution with Water for Injections.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Local injection pain, thrombophlebitis, diarrhea, nausea, mild elevation of AST/ALT. Rare/Severe: Severe anaphylaxis, neutropenia, agranulocytosis, and pseudomembranous colitis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in cephalosporin allergy. Caution in penicillin-allergic patients. Adjust dosage in patients with renal impairment (creatinine clearance < 20 mL/min).
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Cefotaxime Sodium 1g + Sulbactam Sodium 500mg Injection
Cefotaxime Sodium and Sulbactam Sodium is a parenteral combination of a third-generation cephalosporin and a beta-lactamase inhibitor. Cefotaxime inhibits bacterial cell wall synthesis with exceptional activity against Gram-negative bacilli and Streptococcus pneumoniae, while sulbactam neutralizes beta-lactamases produced by resistant pathogens. Indicated for severe intra-abdominal infections, septicemia, meningitis, hospital-acquired pneumonia, and bone and joint infections.
Cefotaxime Sodium 250mg + Sulbactam Sodium 125mg Injection
Cefotaxime Sodium and Sulbactam Sodium is a parenteral combination of a third-generation cephalosporin and a beta-lactamase inhibitor. Cefotaxime inhibits bacterial cell wall synthesis with exceptional activity against Gram-negative bacilli and Streptococcus pneumoniae, while sulbactam neutralizes beta-lactamases produced by resistant pathogens. Indicated for severe intra-abdominal infections, septicemia, meningitis, hospital-acquired pneumonia, and bone and joint infections.
Cefotaxime Sodium 500mg + Sulbactam Sodium 250mg Injection
Cefotaxime Sodium and Sulbactam Sodium is a parenteral combination of a third-generation cephalosporin and a beta-lactamase inhibitor. Cefotaxime inhibits bacterial cell wall synthesis with exceptional activity against Gram-negative bacilli and Streptococcus pneumoniae, while sulbactam neutralizes beta-lactamases produced by resistant pathogens. Indicated for severe intra-abdominal infections, septicemia, meningitis, hospital-acquired pneumonia, and bone and joint infections.
Cefotaxime Sodium Injection 1g
Cefotaxime Sodium is a third-generation parenteral cephalosporin bactericidal antibiotic. It binds to PBPs to inhibit peptidoglycan synthesis. Features high cerebrospinal fluid (CSF) penetration, making it an essential first-line agent for bacterial meningitis. Also indicated for severe sepsis, bacteremia, peritonitis, complicated urinary tract infections, and lower respiratory infections.