Clinical Overview
Ketoconazole (2% w/v, alone or with Zinc Pyrithione 1%) is a topical imidazole broad-spectrum antifungal shampoo. It targets Malassezia furfur (Pityrosporum ovale), the lipophilic yeast implicated in seborrheic dermatitis and pityriasis capitis (dandruff), by inhibiting fungal ergosterol synthesis and reducing scalp scaling, erythema, and pruritus. Indicated for seborrheic dermatitis, stubborn dandruff, and pityriasis (tinea) versicolor of the scalp and trunk.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Wet hair and scalp thoroughly. Apply shampoo and work into a rich lather, massaging into the scalp. Leave on scalp for 3 to 5 minutes before rinsing thoroughly with warm water. Use twice weekly for 2 to 4 weeks for treatment, then once every 1 to 2 weeks for recurrence prevention.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Scalp dryness, mild itching, burning sensation, abnormal hair texture, hair discoloration (in chemically damaged or gray hair). Rare/Severe: Contact dermatitis, scalp pustules, and severe allergic reactions.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
For external topical scalp use only. Keep out of eyes; if contact occurs, rinse immediately with plenty of cool water. Do not stop suddenly if switching from potent topical corticosteroids; taper steroid gradually to avoid rebound erythema.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered dermatologist or qualified medical practitioner before initiating, altering, or substituting any topical or systemic dermatological treatment.