TabletsClinical Overview
Prochlorperazine is a piperazine phenothiazine dopamine D2 antagonist with powerful antiemetic and vestibular-suppressant properties on the WHO Model List of Essential Medicines. It blocks D2 receptors in the chemoreceptor trigger zone (CTZ) of the medulla oblongata and vestibular nuclei, relieving vertigo and suppressing vomiting. Indicated for severe nausea and vomiting, vertigo associated with Meniere's disease or labyrinthitis, and acute migraine attacks.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally with water, with or without meals. For vertigo or nausea, take 2 to 3 times daily as prescribed. For acute nausea, take at the very first onset of symptoms.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Drowsiness, dizziness, dry mouth, blurred vision, mild akathisia. Rare/Severe: Acute dystonic reactions (spasmodic torticollis, facial grimacing, oculogyric crisis, especially in young patients), tardive dyskinesia, and neuroleptic malignant syndrome.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
High risk of acute dystonia in children and adolescents; do not use in children under 2 years of age or weighing < 10 kg. Contraindicated in comatose states or in the presence of large amounts of CNS depressants. Avoid driving.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.