TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2899.
Locate Jan Aushadhi KendraClinical Overview
Selective alpha-1 adrenergic receptor antagonist. It competitively blocks post-junctional alpha-1 receptors on vascular smooth muscle, dilating both arterioles and veins to lower peripheral vascular resistance and systemic blood pressure, while also relaxing smooth muscle in the bladder neck and prostate capsule. Indicated for essential hypertension and benign prostatic hyperplasia (BPH).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily at bedtime with water, with or without food. Bedtime administration of the initial dose is mandatory to prevent "first-dose syncope" and severe postural hypotension.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dizziness, lightheadedness, headache, asthenia, nasal congestion, peripheral edema, somnolence. Rare/Severe: "First-dose phenomenon" (severe postural hypotension and syncope within 30-90 minutes of initial dose), priapism, and Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
First-dose syncope warning: Patients must take the initial dose at bedtime and rise slowly from sitting/lying positions. Inform your ophthalmologist prior to cataract surgery due to IFIS risk.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.