MedicineMRP Under Process
Official PMBI MRP is being updated for catalog code 2870.
Locate Jan Aushadhi KendraClinical Overview
Cefepime is a fourth-generation parenteral cephalosporin bactericidal antibiotic. Its zwitterionic structure allows rapid penetration through Gram-negative bacterial outer membrane porins, providing broad coverage against both Gram-positive organisms (MSSA, streptococci) and Gram-negative bacilli, including Pseudomonas aeruginosa and AmpC-producing Enterobacteriaceae. Indicated for empirical monotherapy in febrile neutropenia, severe hospital-acquired pneumonia, complicated intra-abdominal infections, and complicated pyelonephritis.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administered solely by a registered healthcare professional via deep intramuscular injection or intravenous infusion over 30 minutes after reconstitution with Water for Injections.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Local injection pain, phlebitis, diarrhea, nausea, vomiting, and rash. Rare/Severe: Life-threatening neurotoxicity (encephalopathy, myoclonus, non-convulsive status epilepticus in unadjusted renal dysfunction), anaphylaxis, and aplastic anemia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Critical warning: Neurological toxicity risk in renal failure; strict dose adjustment according to creatinine clearance is vital. Contraindicated in cephalosporin allergy.
Schedule H1 (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
