TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2792.
Locate Jan Aushadhi KendraClinical Overview
Losartan Potassium is the prototype selective competitive angiotensin II receptor type 1 (AT1) antagonist on the WHO Model List of Essential Medicines. It blocks the physiological actions of angiotensin II, lowering systemic vascular resistance and aldosterone secretion, while its active metabolite EXP3174 provides long-acting non-competitive blockade. Possesses unique uricosuric activity, lowering serum uric acid levels. Indicated for essential hypertension, diabetic nephropathy in type 2 diabetes with elevated creatinine and proteinuria, and stroke reduction in hypertensive patients with left ventricular hypertrophy.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once or twice daily with water, with or without food. Maintain regular daily dosing. Do not stop abruptly.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Dizziness, nasal congestion, back pain, fatigue, upper respiratory tract infection. Rare/Severe: Boxed warning: Fetal toxicity; angioedema (swelling of face, lips, tongue), hyperkalemia, acute kidney injury in renal artery stenosis, and hypotension.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Fetal toxicity; discontinue immediately if pregnancy is diagnosed. Monitor serum potassium, especially when taking potassium-sparing diuretics or ACE inhibitors. Caution in volume-depleted patients.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified cardiologist/pharmacist before initiating, altering, or substituting any cardiovascular medication.
Amlodipine 5mg + Atenolol 50mg Tablets
Amlodipine and Atenolol is a classic dual-mechanism cardiovascular combination pairing a dihydropyridine calcium channel blocker with a cardioselective beta-1 blocker. Amlodipine lowers peripheral vascular resistance and dilates coronary arteries, while atenolol reduces resting and exercise heart rates, suppresses cardiac contractility, and eliminates the reflex tachycardia typically triggered by dihydropyridine vasodilation. Indicated for essential hypertension and stable chronic angina pectoris.
Atenolol Tablets 50 mg
Beta-adrenergic receptor antagonist (cardioselective beta-1 blocker, non-selective beta blocker, or third-generation vasodilating beta-blocker with alpha-blockade or nitric oxide release) on the WHO Model List of Essential Medicines. It competitively blocks adrenergic stimulation, reducing heart rate, myocardial contractility, cardiac output, and renin release. Indicated for hypertension, stable angina pectoris, heart failure, cardiac arrhythmias, and post-myocardial infarction secondary prevention.
Losartan Potassium 50mg + Hydrochlorothiazide 12.5mg Tabelts
Losartan Potassium and Hydrochlorothiazide combines a selective AT1 receptor blocker with a thiazide diuretic on the WHO Model List of Essential Medicines. Losartan blocks angiotensin II-induced vasoconstriction and uniquely possesses intrinsic uricosuric properties that increase uric acid excretion, offsetting the hyperuricemic tendency of hydrochlorothiazide, while hydrochlorothiazide reduces extracellular fluid volume. Indicated for the treatment of hypertension not adequately controlled on monotherapy and for reducing stroke risk in hypertensive patients with left ventricular hypertrophy.
Losartan Tablets 25mg
Losartan Potassium is the prototype selective competitive angiotensin II receptor type 1 (AT1) antagonist on the WHO Model List of Essential Medicines. It blocks the physiological actions of angiotensin II, lowering systemic vascular resistance and aldosterone secretion, while its active metabolite EXP3174 provides long-acting non-competitive blockade. Possesses unique uricosuric activity, lowering serum uric acid levels. Indicated for essential hypertension, diabetic nephropathy in type 2 diabetes with elevated creatinine and proteinuria, and stroke reduction in hypertensive patients with left ventricular hypertrophy.